Review of pyronaridine anti-malarial properties and product characteristics. [PDF]
, 2012 Pyronaridine was synthesized in 1970 at the Institute of Chinese Parasitic Disease and has been used in China for over 30 years for the treatment of malaria.
Arbe-Barnes, Sarah J +7 more
core +2 more sources
Two-year follow-up of macaques developing intermittent control of the human immunodeficiency virus homolog simian immunodeficiency virus SIVmac251 in the chronic phase of infection [PDF]
, 2015 Off-therapy control of viremia by HIV-infected individuals has been associated with two likely players: a restricted viral reservoir and an efficient cell-mediated immune response.
Arts, Eric +14 more
core +2 more sources
Initial combination therapy of macitentan and tadalafil in pulmonary arterial hypertension
European Respiratory Journal, 2020 Initial combination therapy plays a central role in managing pulmonary arterial hypertension (PAH) [1–4]. Patients with low- or intermediate-risk of 1-year mortality at diagnosis should be treated with initial combination therapy with an endothelin ...
O. Sitbon +11 more
semanticscholar +1 more source
PHOTODYNAMIC THERAPY FOR LUNG CANCER: MAJOR INDICATIONS
Сибирский онкологический журнал, 2016 Lung cancer treatment remains a major challenge for modern oncology. Photodynamic therapy (PDT) has proved to be an effective anti-tumor treatment modality for patients with lung cancer. This paper evaluated results of using PDT for lung cancer patients.
Yu. A. Ragulin, V. N. Galkin
doaj +1 more source
A synthetic-lethality RNAi screen reveals an ERK-mTOR co-targeting pro-apoptotic switch in PIK3CA+ oral cancers. [PDF]
, 2016 mTOR inhibition has emerged as a promising strategy for head and neck squamous cell carcinomas (HNSCC) treatment. However, most targeted therapies ultimately develop resistance due to the activation of adaptive survival signaling mechanisms limiting the ...
Amornphimoltham, Panomwat +10 more
core +1 more source
Olmesartan-based monotherapy vs combination therapy in hypertension: A meta-analysis based on age and chronic kidney disease status. [PDF]
, 2017 Antihypertensive monotherapy is often insufficient to control blood pressure (BP). Several recent guidelines advocate for initial combination drug therapy in many patients. This meta-analysis of seven randomized, double-blind studies (N = 5888) evaluated
Bakris, George +3 more
core +1 more source
Nature Communications, 2022 A 30-year-old bombing victim with a fracture-related pandrug-resistant Klebsiella pneumoniae infection after long-term (>700 days) antibiotic therapy is treated with a pre-adapted bacteriophage along with meropenem and colistin, followed by ceftazidime ...
Anaïs Eskenazi +17 more
semanticscholar +1 more source
Nanoparticle-Assisted Sonosensitizers and Their Biomedical Applications
International Journal of Nanomedicine, 2021 Pengxuan Zhao,1 Youbin Deng,1 Guangya Xiang,2 Yani Liu1 1Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, People’s Republic of China; 2School of Pharmacy, Tongji ...
Zhao P, Deng Y, Xiang G, Liu Y
doaj
Nanoparticle-Based Combination Therapy for Melanoma
Frontiers in Oncology, 2022 Melanoma is a cutaneous carcinoma, and its incidence is rapidly increasing with every year. The treatment options for melanoma have been comprehensively studied.
Hongbo Chen +4 more
doaj +1 more source
Autophagy Modulation and Cancer Combination Therapy: A Smart Approach in Cancer Therapy
Cancer Treatment and Research Communications, 2022 The autophagy pathway is the process whereby cells keep cellular homeostasis and respond to stress via recycling their damaged cellular proteins, organelles, and other cellular components. In the context of cancer, autophagy is a dual-edge sword pro- and
Ali Salimi-Jeda +8 more
doaj