Results 51 to 60 of about 2,606,922 (264)

Co-Delivery of Paclitaxel Prodrug, Gemcitabine and Porphine by Micelles for Pancreatic Cancer Treatment via Chemo-Photodynamic Combination Therapy

Pharmaceutics, 2022
Pancreatic carcinoma is an aggressive subtype of cancer with poor prognosis, known for its refractory nature. To address this challenge, we have established a stable nanoplatform that combines chemotherapy with photodynamic therapy (PDT) to achieve ...
Qiwei Wu, Xiaodong Ma, Wenhui Zhou, Rong Yu, Jessica M. Rosenholm, Weizhong Tian, Lirong Zhang, Dongqing Wang, Hongbo Zhang   +8 more
doaj   +1 more source

Costing Artemisinin-based Combination Therapy for Malaria in Tanzania [PDF]

, 2005
Malaria continues to be a major contributor to the burden of disease in Tanzania, with a prevalence of 33.39 percent nationally. As antimalarial resistance to sulfadoxine-pyrimethamine in Tanzania continues to grow, the government is in the process of ...
Derriennic, Yann, Wolf, Katherine
core  

Injectable Polypeptide Hydrogel Depots Containing Dual Immune Checkpoint Inhibitors and Doxorubicin for Improved Tumor Immunotherapy and Post-Surgical Tumor Treatment

Pharmaceutics, 2023
In this work, we developed a strategy for local chemo-immunotherapy through simultaneous incorporation of dual immune checkpoint blockade (ICB) antibodies, anti-cytotoxic T-lymphocyte-associated protein 4 (aCTLA-4) and anti-programmed cell death protein ...
Zhixiong Chen, Yan Rong, Junfeng Ding, Xueliang Cheng, Xuesi Chen, Chaoliang He   +5 more
doaj   +1 more source

Targeting tumour re-wiring by triple blockade of mTORC1, epidermal growth factor, and oestrogen receptor signalling pathways in endocrine-resistant breast cancer [PDF]

, 2018
Background Endocrine therapies are the mainstay of treatment for oestrogen receptor (ER)-positive (ER+) breast cancer (BC). However, resistance remains problematic largely due to enhanced cross-talk between ER and growth factor pathways, circumventing ...
A Carracedo, A Subramanian, AH Evans, Allan Thornhill, Alshad S. Lalani, Aradhana Rani, C Trapnell, CK Osborne, CX Ma, Eugene Schuster, FL Chen, Francesca Avogadri-Connors, G Arpino, HJ Burstein, IE Smith, J Baselga, Joanna Nikitorowicz-Buniak, KE Bachman, KE O'Reilly, L Gandhi, LA Martin, LA Martin, Lesley-Ann Martin, LV Sequist, M Arnedos, M Dowsett, Mitch Dowsett, MT Weigel, N Patani, N Simigdala, NA O'Brien, Nikiana Simigdala, R Ribas, Ricardo Ribas, Richard E. Cutler, S Johnston, SC Drury, SN Mohd Nafi, SP Newman, Stephanie K. Guest, Stephen R. Johnston, Sunil Pancholi, T Nagashima, W Luo   +43 more
core   +6 more sources

Understanding and targeting resistance mechanisms in cancer

MedComm, 2023
Resistance to cancer therapies has been a commonly observed phenomenon in clinical practice, which is one of the major causes of treatment failure and poor patient survival. The reduced responsiveness of cancer cells is a multifaceted phenomenon that can
Zi‐Ning Lei, Qin Tian, Qiu‐Xu Teng, John N. D. Wurpel, Leli Zeng, Yihang Pan, Zhe‐Sheng Chen   +6 more
doaj   +1 more source

Adherence to self-administered tuberculosis treatment in a high HIV-prevalence setting: a cross-sectional survey in Homa Bay, Kenya. [PDF]

, 2012
Good adherence to treatment is crucial to control tuberculosis (TB). Efficiency and feasibility of directly observed therapy (DOT) under routine program conditions have been questioned.
AK Person, Apollo Odongo Aloo, B Blomberg, C Lienhardt, Claire Thorne, DK Mafigiri, DR Bangsberg, DR Bangsberg, Emmanuelle Espié, FA Kaona, Fabienne Nackers, Francis Varaine, G Fochsen, G Verma, H Huerga, Helena Huerga, J Connor, J Elizaga, J Macq, J Sim, J Volmink, Jean-François Etard, Jeremiah Chakaya, JH Oyugi, Joseph Sitienei, KR Amico, L Osterberg, L Tuyisenge, Maryline Bonnet, Mathieu Bastard, ME Raguenaud, MJ Selgelid, MS Pepe, N Awofeso, PE Meissner, R Steffen, RA Atun, S Bangalore, S Mannheimer, SA Munro, SB Mannheimer, SC Kalichman, SM Youngleson, TA Szakacs, TP Giordano, W Xu, WA Kaplan   +46 more
core   +5 more sources

Combination Drug Therapy for Benign Prostatic Hyperplasia (BPH)

The Annals of African Surgery, 2010
Background: The incidence of benign prostatic hyperplasia peaks 80% in old age. Bothersome symptoms and progression to acute urinary retention and need for surgery are important concerns.
Oliech J.S.
doaj  

A Systematic Review of therapeutic agents for the treatment of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) [PDF]

, 2019
Background The Middle East Respiratory Syndrome Coronavirus (MERS-CoV) was first described in 2012 and attracted a great international attention due to multiple healthcare associated outbreaks.
Al-Ali, Anfal Y., Al-Tawfiq, Jaffar A., Momattin, Hisham   +2 more
core   +1 more source

COMBINATION ANTIHYPERTENSION THERAPY: TRIPLE FIXED COMBINATION OF ANTIHYPERTENSIVE DRUGS

Российский кардиологический журнал, 2017
The article presents modern view on the role of combination antihypertension therapy in treatment of arterial hypertension. The benefits of fixed combinations are shown, rational combinations described for three antihypertensive medications.
O. D. Ostroumova, V. V. Vikentiev, T. F. Guseva   +2 more
doaj   +1 more source

An Overlap Analysis of Occupational Therapy Electronic Journals Available in Full-Text Databases and Subscription Services [PDF]

, 2008
In order to convert occupational therapy journal subscriptions from print to electronic, a university library, in collaboration with its Occupational Therapy Program, compared full-text databases and journal subscription services.
Schroeder, Judy
core   +3 more sources