Results 51 to 60 of about 9,546,669 (393)

Anti-tumor Mechanism of Sonodynamic Combined with Hyperthermia and Its Application in Tumor

Zhongliu Fangzhi Yanjiu, 2022
Sonodynamic therapy (SDT) is a new non-invasive treatment method that uses a combination of sono-sensitizers and low-intensity ultrasound (US) to treat malignant tumors. SDT is developed from photodynamic therapy (PDT).
HAN Jiaxuan, ZHAO Yun
doaj   +1 more source

MTOR cross-talk in cancer and potential for combination therapy [PDF]

, 2018
The mammalian Target of Rapamycin (mTOR) pathway plays an essential role in sensing and integrating a variety of exogenous cues to regulate cellular growth and metabolism, in both physiological and pathological conditions.
Bazzichetto, C., Bria, E., Ciuffreda, L., Cognetti, F., Conciatori, F., Falcone, I., Milella, M, Pilotto, S.   +7 more
core   +3 more sources

Life expectancy of persons receiving combination antiretroviral therapy in low-income countries: a cohort analysis from Uganda [PDF]

, 2011
Little is known about the effect of combination antiretroviral therapy (cART) on life expectancy in sub-Saharan ...
Bakanda, Celestin, Birungi, Josephine, Chan, Keith, Cooper, Curtis L, Dybul, Mark, Ford, Nathan, Hogg, Robert S, Mills, Edward J, Nachega, Jean B   +8 more
core   +2 more sources

Combination Therapy Is Not Associated with Decreased Mortality in Infectious Endocarditis: A Systematic Review and Meta-Analysis

Microorganisms
Untreated infective endocarditis (IE) is uniformly fatal. The practice of combination antibiotic therapy for IE is recommended by treatment guidelines but largely unsupported by high-quality evidence.
Parisa Farahani, Felicia Ruffin, Mohammad Taherahmadi, Maren Webster, Rachel E. Korn, Sarah Cantrell, Lana Wahid, Vance G. Fowler, Joshua T. Thaden   +8 more
doaj   +1 more source

Modern Principles of Treatment of Uncontrolled Hypertension

Рациональная фармакотерапия в кардиологии, 2019
Despite the current possibilities of using different classes of antihypertensive drugs that effectively reduce blood pressure and significantly improve the long-term prognosis of patients, the problem of uncontrolled arterial hypertension has not lost ...
V. I. Podzolkov, A. I Tarzimanova, Z. O. Georgadze   +2 more
doaj   +1 more source

Roles of STAT3 in the pathogenesis and treatment of glioblastoma

Frontiers in Cell and Developmental Biology, 2023
Glioblastoma (GBM) is the most malignant of astrocytomas mainly involving the cerebral hemispheres and the cerebral cortex. It is one of the fatal and refractory solid tumors, with a 5-year survival rate of merely 5% among the adults. IL6/JAK/STAT3 is an
Weijia Fu, Weijia Fu, Weijia Fu, Xue Hou, Xue Hou, Xue Hou, Lihua Dong, Lihua Dong, Lihua Dong, Wei Hou, Wei Hou, Wei Hou   +11 more
doaj   +1 more source

Overall survival of patients with recurrent pancreatic cancer treated with systemic therapy: a retrospective study [PDF]

, 2019
BACKGROUND: Only a few patients with pancreatic ductal adenocarcinoma (PDAC) recurring after curative resection and peri-operative (neoadjuvant and adjuvant) therapy are included in clinical trials of metastatic PDAC.
Gbolahan, Olumide B., O’Neil, Bert, Sehdev, Amikar, Shahda, Safi, Tong, Yan   +4 more
core   +1 more source

Efficacy of Elaborated Semantic Features Analysis in Aphasia: a quasi-randomised controlled trial [PDF]

, 2019
Background: Word finding difficulty is one of the most common features of aphasia. Semantic Features Analysis (SFA) directly aims to improve word finding in people with aphasia.
Elman R., Evangelia-Antonia Efstratiadou, Fisher L. D., Frattali C. M., Frattali C. M., Goodglass H., Ilias Papathanasiou, Kartsona A., Katerina Hilari, Papathanasiou I., Papathanasiou I., Rachel Holland, Spyridoula Varlokosta, World Health Organisation   +13 more
core   +1 more source

Combination Therapies for Obesity [PDF]

Metabolic Syndrome and Related Disorders, 2018
The objective of this review is to examine advances in the development of combination therapies for the treatment of obesity beyond diet or lifestyle interventions. Experimental combination pharmacotherapies include combinations of pramlintide and phentermine as well as amylin and bupropion-naltrexone. Incretin and pancreatic hormones generally inhibit
Andres Acosta, Michael Camilleri
openaire   +2 more sources

FoxO1 signaling in B cell malignancies and its therapeutic targeting

FEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac, Petra Pavelkova, Laura Ondrisova, Marek Mraz   +3 more
wiley   +1 more source