Results 151 to 160 of about 227 (197)

In silico modelling of multi‐electrode arrays for enhancing cardiac drug testing on hiPSC‐CM heterogeneous tissues

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the experimental and computational framework for investigating hiPSC‐CM electrophysiology with MEA systems. The MEA‐based model integrates experimental data with phenotype‐specific ionic models and tissue‐level heterogeneity.
Sofia Botti   +2 more
wiley   +1 more source

A Simulation Study on Spatial Exponential Decay of Perturbations in a Two‐Dimensional Wave Equation With Optimal Boundary/Line Control

open access: yesProceedings in Applied Mathematics and Mechanics, Volume 26, Issue 4, December 2026.
ABSTRACT Recent results have shown that domain‐uniform stabilizability and detectability imply spatial exponential decay of perturbations in optimally controlled hyperbolic PDEs on one‐dimensional domains. This domain‐uniform stabilizability and detectability can be achieved only if the control domain is distributed over the whole spatial domain such ...
Benedikt Oppeneiger
wiley   +1 more source

On the additive image of zeroth persistent homology

open access: yesTransactions of the London Mathematical Society, Volume 13, Issue 1, December 2026.
Abstract For a category X$X$ and a finite field F$F$, we study the additive image of the functor H0(−;F)∗:rep(X,Top)→rep(X,VectF)$\operatorname{H}_0(-;F)_* \colon \operatorname{rep}(X, \mathbf {Top}) \rightarrow \operatorname{rep}(X, \mathbf {Vect}_F)$, or equivalently, of the free functor rep(X,Set)→rep(X,VectF)$\operatorname{rep}(X, \mathbf {Set ...
Ulrich Bauer   +3 more
wiley   +1 more source

Generalizing the Gaussian Network Model: Spanning‐Tree Thermodynamics Shows Entropy‐Driven KRAS Activation

open access: yesProteins: Structure, Function, and Bioinformatics, Volume 94, Issue 10, Page 1671-1685, October 2026.
ABSTRACT The GTPase KRAS executes a conformational switch between a GTP‐bound active state and a GDP‐bound inactive state, a process central to oncogenic signaling. However, the structural basis of this switching at the level of residue‐contact organization remains incompletely characterized by traditional binary structural models.
Fatma Senguler Ciftci, Burak Erman
wiley   +1 more source

Mandated Annuitization, Gender‐Neutral Pricing, and the Possibility of Negative Correlation Between Risk Type and Purchase Level

open access: yesJournal of Public Economic Theory, Volume 28, Issue 5, October 2026.
ABSTRACT Mandated annuitization is often proposed to eliminate the inefficiency caused by the positive correlation between risk type and purchase level in insurance markets. We revisit this solution in a mandatory annuity program with partial waiver, which is empirically relevant.
Sau‐Him Paul Lau   +2 more
wiley   +1 more source

Solving Stochastic Climate‐Economy Models: A Deep Least‐Squares Monte Carlo Approach

open access: yesMathematical Finance, Volume 36, Issue 4, Page 751-770, October 2026.
ABSTRACT Stochastic versions of recursive integrated climate‐economy assessment models are essential for studying and quantifying policy decisions under uncertainty. However, as the number of state variables and stochastic shocks increases, solving these models via deterministic grid‐based dynamic programming (e.g., value‐function iteration/projection ...
Aleksandar Arandjelović   +4 more
wiley   +1 more source

Hybrid Coupling With Operator Inference and the Overlapping Schwarz Alternating Method

open access: yesInternational Journal for Numerical Methods in Engineering, Volume 127, Issue 17, 15 September 2026.
ABSTRACT This paper presents a hybrid approach for coupling subdomain‐local, nonintrusive Operator Inference (OpInf) reduced order models (ROMs) with each other and with subdomain‐local, high‐fidelity full order models (FOMs) using the overlapping Schwarz alternating method (O‐SAM).
Irina Tezaur   +5 more
wiley   +1 more source

Machine‐Learning Enhanced Parametric Reynolds‐Averaged Navier‐Stokes Equations at the Full‐ and Reduced‐Order Levels

open access: yesInternational Journal for Numerical Methods in Engineering, Volume 127, Issue 17, 15 September 2026.
ABSTRACT In this contribution, we focus on the Reynolds‐averaged Navier‐Stokes (RANS) models and their exploitation to build reliable reduced‐order models to further accelerate predictions for real‐time applications and many‐query scenarios. Specifically, we investigate how machine learning can be employed to enhance the predictive capabilities of the ...
Davide Oberto   +2 more
wiley   +1 more source

A new drag and lift correlation for spherocylinders from fully resolved Immersed Boundary Method

open access: yesAIChE Journal, Volume 72, Issue 9, September 2026.
Abstract Many industrial processes deal with non‐spherical particles, e.g., mineral mining and biomass conversion. It is crucial to understand the particles' hydrodynamics to control and optimize these processes. To extend the current state‐of‐the‐art from arrays of spherical particles to spherocylindrical particles, we performed extensive particle ...
A. H. Huijgen   +4 more
wiley   +1 more source

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