Results 171 to 180 of about 1,144,978 (368)

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

open access: yesMolecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton   +17 more
wiley   +1 more source

Hit-optimization using target-directed dynamic combinatorial chemistry: development of inhibitors of the anti-infective target 1-deoxy-d-xylulose-5-phosphate synthase. [PDF]

open access: yesChem Sci, 2021
Jumde RP   +12 more
europepmc   +1 more source

Cleavage Automated: A New Combinatorial Chemistry Tool [PDF]

open access: bronze, 2000
Nicholas Cook, Ken Young, A. L. STANLEY
openalex   +1 more source

Localized template-driven functionalization of nanoparticles by dynamic combinatorial chemistry.

open access: yesAngewandte Chemie, 2015
P. Nowak   +5 more
semanticscholar   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

The dark side of disulfide-based dynamic combinatorial chemistry. [PDF]

open access: yesChem Sci, 2020
Dumartin M   +7 more
europepmc   +1 more source

Support Vector Machines in Combinatorial Chemistry

open access: yesMeasurement + Control, 2001
Matthew W B Trotter   +2 more
doaj   +1 more source

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