Results 171 to 180 of about 1,058,395 (336)

Target-Directed Dynamic Combinatorial Chemistry Affords Binders of Mycobacterium tuberculosis IspE. [PDF]

ACS Omega
Braun-Cornejo M, Ornago C, Sonawane V, Haupenthal J, Kany AM, Diamanti E, Jézéquel G, Reiling N, Blankenfeldt W, Maas P, Hirsch AKH.   +10 more
europepmc   +1 more source

Papers on combinatorial chemistry or solid-phase synthesis from other journals - November 2000

, 2000

openalex   +1 more source

Synthesis of Gd[sub 2]O[sub 3]:Eu, Li Phosphor by Modified Combinatorial Chemistry and Its Photoluminescence Behavior [PDF]

, 2002
Joung Kyu Park, Sang Mi Park, Chang Hae Kim, Hee Dong Park, Se Young Choi   +4 more
openalex   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

Molecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed, Lucas Mani, Muhammad Bilal Mirza, Ashtyn McAdoo, Takahito Kondo, Hidenori Tanaka, Nicole Meeks, Eben Rosenthal, Marisa Hom   +8 more
wiley   +1 more source

Evolution Driven Microscale Combinatorial Chemistry in Intracellular Mimicking Droplets to Engineer Thermostable RNA for Cellular Imaging. [PDF]

Small
Kinghorn AB, Guo W, Wang L, Tang MYH, Wang F, Shiu SC, Lau KK, Jinata C, Poonam AD, Shum HC, Tanner JA.   +10 more
europepmc   +1 more source

Papers on combinatorial chemistry or solid-phase synthesis from other journals - September 2000

, 2000

openalex   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

Molecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski, Molly R. Danks, John P. Thomson, Morwenna Muir, Martin Lee, John C. Dawson, Ana T. Amaral, Juan Diaz‐Martin, David S. Moura, Javier Martin‐Broto, Ali Alsaadi, Donald M. Salter, Ailsa J. Oswald, Graeme Grimes, Larry Hayward, Ted R. Hupp, Karen Sisley, Paul H. Huang, Neil O. Carragher, Valerie G. Brunton   +19 more
wiley   +1 more source

Pioneering integration of combinatorial chemistry and machine learning to accelerate the development of tailored LNPs for mRNA delivery. [PDF]

Acta Pharm Sin B
He X, Wang P, Qing L, Song X.
europepmc   +1 more source

Papers on combinatorial chemistry or solid-phase synthesis from other journals - April 2000

, 2000

openalex   +1 more source

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

Molecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany   +9 more
wiley   +1 more source