β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
ErB4 and NdB4 nanostructured powders are produced by mechanochemical synthesis. 5 h mechanical alloying and 4 M HCl acid leaching are used in the production. ErB4 and NdB4 powders exhibit maximum magnetization of 0.4726 emu g−1 accompanied with an antiferromagnetic‐to‐paramagnetic phase transition at about TN = 18 K and 0.132 emu g−1 with a maximum at ...
Burçak Boztemur +5 more
wiley +1 more source
Accelerate the Highly Efficient Development of mRNA Vaccines Through Advanced Computational Methods. [PDF]
Gu R, Si D, Lei D, Xie X, Li Y, Wen H.
europepmc +1 more source
What Do Large Language Models Know About Materials?
If large language models (LLMs) are to be used inside the material discovery and engineering process, they must be benchmarked for the accurateness of intrinsic material knowledge. The current work introduces 1) a reasoning process through the processing–structure–property–performance chain and 2) a tool for benchmarking knowledge of LLMs concerning ...
Adrian Ehrenhofer +2 more
wiley +1 more source
Imaging-Based Spatial Transcriptomics: Data Interpretation Methods and Biomedical Applications. [PDF]
Li W, Zhou Y.
europepmc +1 more source
In this review, the current state of light‐assisted 3D printing as it pertains to engineering musculoskeletal tissues including bone, cartilage, skeletal muscle, tendon, and ligaments is summarized. Common printing techniques, photoreactive materials, and study design choices are compiled and reviewed.
Meagan Morgan, Bin Zhang, Roger Narayan
wiley +1 more source
Energy-Screened Many-Body Expansion for Protein-Ligand Interactions: Examining Convergence for Metalloenzymes Through Seven-Body Interactions. [PDF]
Bowling PE, Broderick DR, Herbert JM.
europepmc +1 more source
Emerging strategies to enhance microbial natural product-based drug discovery. [PDF]
Madden M +4 more
europepmc +1 more source
Accelerating Combinatorial Electrocatalyst Discovery with Bayesian Optimization: a Case Study in the Quaternary System Ni-Pd-Pt-Ru for the Oxygen Evolution Reaction. [PDF]
Thelen F +6 more
europepmc +1 more source
Motif caller for sequence reconstruction in motif-based DNA storage. [PDF]
Agarwal P, Pinnamaneni N, Heinis T.
europepmc +1 more source

