Results 81 to 90 of about 9,474,722 (291)

Optimal Combinatorial Electricity Markets

, 2008
The deregulation of the electricity industry in many countries has created a number of marketplaces in which producers and consumers can operate in order to more effectively manage and meet their energy needs. To this end, this paper develops a new model
Jennings, N. R., Penya, Y.K.
core   +1 more source

A combinatorial approach to the design of vaccines

Journal of Mathematical Biology, 2014
We present two new problems of combinatorial optimization and discuss their applications to the computational design of vaccines. In the shortest λ-superstring problem, given a family S1,...,S(k) of strings over a finite alphabet, a set Τ of "target" strings over that alphabet, and an integer λ, the task is to find a string of minimum length containing,
Martínez, Luis, Milanič, Martin, Legarreta Solaguren, Leire, Medvedev, Paul, Malaina, Iker, Fuente, Ildefonso M. de la   +5 more
openaire   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

The Clock-Proxy Auction: A Practical Combinatorial Auction Design [PDF]

We propose the clock-proxy auction as a practical means for auctioning many related items. A clock auction phase is followed by a last-and-final proxy round.
Peter Cramton, Lawrence M. Ausubel, Paul Milgrom   +2 more
core  

Limits on Computationally Efficient VCG-Based Mechanisms for Combinatorial Auctions and Public Projects [PDF]

, 2011
A natural goal in designing mechanisms for auctions and public projects is to maximize the social welfare while incentivizing players to bid truthfully.
Buchfuhrer, David Isaac
core   +1 more source

Natural product-like combinatorial libraries

Journal of the Brazilian Chemical Society, 2003
Combinatorial chemistry has emerged over the last few years as an important tool for drug discovery and lead optimisation. In this approach, the molecular diversity and range of biological properties displayed by secondary metabolites constitutes a ...
Abreu Pedro M., Branco Paula S.
doaj  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Price-Based Combinatorial Auction Design: Representative Valuations [PDF]

We investigate price-based mechanisms with connectedness in combinatorial auctions, where with restrictions of privacy and complexity, the auctioneer asks a limited number of prices to buyers who provide demand responses.
Hitoshi Matsushima
core  

Quick design of feasible tensor networks for constrained combinatorial optimization [PDF]

Quantum
Quantum computers are expected to enable fast solving of large-scale combinatorial optimization problems. However, their limitations in fidelity and the number of qubits prevent them from handling real-world problems.
Hyakka Nakada, Kotaro Tanahashi, Shu Tanaka   +2 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source