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On combinatorial DNA word design
Journal of Computational Biology, 2000We consider the problem of designing DNA codes, namely sets of equi-length words over the alphabet [A, C, G, T] that satisfy certain combinatorial constraints. This problem is motivated by the task of reliably storing and retrieving information in synthetic DNA strands for use in DNA computing or as molecular bar codes in chemical libraries.
Amit Marathe +2 more
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Design issues for combinatorial auctions
4OR, 2021zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Jawad Abrache +2 more
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A combinatorial design approach to MAXCUT
Random Structures and Algorithms, 1996zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Thomas Hofmeister, Hanno Lefmann
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Current Opinion in Structural Biology, 2002
Combinatorial protein libraries permit the examination of a wide range of sequences. Such methods are being used for denovo design and to investigate the determinants of protein folding. The exponentially large number of possible sequences, however, necessitates restrictions on the diversity of sequences in a combinatorial library.
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Combinatorial protein libraries permit the examination of a wide range of sequences. Such methods are being used for denovo design and to investigate the determinants of protein folding. The exponentially large number of possible sequences, however, necessitates restrictions on the diversity of sequences in a combinatorial library.
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The Design of Leadlike Combinatorial Libraries
Angewandte Chemie International Edition, 1999The optimization of low-potency leads into drugs is often accompanied by an increase in molecular weight (M(r)) and lipophilicity, as a consequence of affinity enhancement. Hits with affinity at µM levels discovered by screening leadlike libraries allow scope for this optimization process, as shown schematically by the distributions of M(r) for a ...
, Teague, , Davis, , Leeson, , Oprea
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Combinatorial test design in practice
Proceedings of the 32nd ACM/IEEE International Conference on Software Engineering - Volume 2, 2010Combinatorial testing is a specification based sampling technique that provides a systematic way to select combinations of program inputs or features for testing. It has been applied over the years to test input data, configurations, web forms, protocols, graphical user interfaces and for testing software product lines.
Myra B. Cohen, Shmuel Ur
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Combinatorial aspects of automated designs
Proceedings of the SHARE design automation project on - DAC '66, 1966One of the characteristic problems involved in design is geometric arrangement. Components must be fitted onto a circuit card, or rooms must be fitted together to form a livable house, subject to certain constraints. These arrangement problems appear particularly difficult when viewed from the stand point of the traditional tools of mathematical ...
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Combinatorial Information Market Design
Information Systems Frontiers, 2003Information markets are markets created to aggregate information. Such markets usually estimate a probability distribution over the values of certain variables, via bets on those values. Combinatorial information markets would aggregate information on the entire joint probability distribution over many variables, by allowing bets on all variable value ...
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