Results 41 to 50 of about 70,607 (282)

Why and When Are Evidence‐Based Interventions Adopted in Paediatric Supportive Care? A Qualitative Exploration of the Determinants of Photobiomodulation Implementation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Oral mucositis is a common and debilitating side effect of childhood cancer and stem cell transplant treatments. It affects the quality of life of children and young people (CYP) and places a strain on services. Photobiomodulation is recommended for oral mucositis prevention in international guidance but is poorly implemented in UK ...
Claudia Heggie, Kara A. Gray‐Burrows, Peter F. Day, Bob Phillips, Carl A. Thompson   +4 more
wiley   +1 more source

A feasibility approach for constructing combinatorial designs of circulant type [PDF]

, 2017
In this work, we propose an optimization approach for constructing various classes of circulant combinatorial designs that can be defined in terms of autocorrelations.
Artacho, Francisco J. Aragón, Campoy, Rubén, Kotsireas, Ilias, Tam, Matthew K.   +3 more
core   +3 more sources

Real‐World Pediatric Blinatumomab Administration: Access to Outpatient Care Delivery and Impact of a Hospital‐Dispensed Model

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Blinatumomab has been shown to be highly effective for patients with pediatric B‐ALL and has recently become standard of care therapy. Due to its past use in the clinical trial setting, there is limited information available about real‐world administration.
Katelyn Oranges, Kelly A. Duffy, Sara McDonough, Evelyn Kurpiewski, R. Jennifer Randall, Allison Barz Leahy, Haley M. Newman, Joyce P. Lee, Stephen P. Hunger, Anne F. Reilly, David T. Teachey, Susan R. Rheingold, Daniel J. Zheng   +12 more
wiley   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Transitive combinatorial structures invariant under some subgroups of S(6,2) and related codes

Atti della Accademia Peloritana dei Pericolanti : Classe di Scienze Fisiche, Matematiche e Naturali, 2018
In this paper we define combinatorial structures on the conjugacy classes of the maximal subgroups of the symplectic group S(6,2) under the action of two subgroups of S(6,2) isomorphic to U(3,3) or U(4,2).
Dean Crnković, Vedrana Mikulić Crnković, Andrea Švob   +2 more
doaj   +1 more source

Additive combinatorial designs

Designs, Codes and Cryptography
Abstract A $$2-(v, k, \lambda )$$ 2 - ( v , k , λ )
Buratti M., Merola F., Nakic A.
openaire   +2 more sources

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

Population-specific design of de-immunized protein biotherapeutics. [PDF]

PLoS Computational Biology, 2018
Immunogenicity is a major problem during the development of biotherapeutics since it can lead to rapid clearance of the drug and adverse reactions. The challenge for biotherapeutic design is therefore to identify mutants of the protein sequence that ...
Benjamin Schubert, Charlotta Schärfe, Pierre Dönnes, Thomas Hopf, Debora Marks, Oliver Kohlbacher   +5 more
doaj   +1 more source

Generalized covering designs and clique coverings

, 2011
Inspired by the "generalized t-designs" defined by Cameron [P. J. Cameron, A generalisation of t-designs, Discrete Math. 309 (2009), 4835--4842], we define a new class of combinatorial designs which simultaneously provide a generalization of both ...
Bailey, Robert F., Burgess, Andrea C., Cavers, Michael S., Meagher, Karen   +3 more
core   +2 more sources

Combinatorial design of pseudoknot RNA

Advances in Applied Mathematics, 2009
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Emma Yu Jin, Christian M. Reidys
openaire   +2 more sources