Results 61 to 70 of about 864,970 (299)
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono +7 more
wiley +1 more source
Combinatorial design of textured mechanical metamaterials [PDF]
Main text: 5 p, 3 figs.
Coulais, C.J. +4 more
openaire +4 more sources
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Geometrical Theory on Combinatorial Manifolds [PDF]
Topological and differential structures such as those of d-pathwise connected, homotopy classes, fundamental d-groups in topology and tangent vector fields, tensor fields, connections, Minkowski norms in differential geometry on these finitely ...
Mao, Linfan
core +1 more source
Note on Certain Combinatorial Designs [PDF]
Let v, ,i, n and Xn be integers such that v > 1> 1, n > 1 and Xn _1 By a (Xn, n, P,, v) tactical configuration is meant an arrangement of v objects into certain blocks such that each block consists of pi distinct objects and that each set of n objects occurs together in exactly AXn blocks [3, p. 264].
openaire +2 more sources
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa +7 more
wiley +1 more source
Population-specific design of de-immunized protein biotherapeutics. [PDF]
Immunogenicity is a major problem during the development of biotherapeutics since it can lead to rapid clearance of the drug and adverse reactions. The challenge for biotherapeutic design is therefore to identify mutants of the protein sequence that ...
Benjamin Schubert +5 more
doaj +1 more source
Completion and Embedding Problems for Combinatorial Designs
Combinatorial design theory studies arrangements and combinations of discrete objects according to different rules. Applications of designs are not only limited to analysis of experiments, but also useful in network analysis, cryptography and ...
AJANI RUWANDHIKA CHULANGI DE VAS GUNASEKARA (13207959)
core +1 more source
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source

