Results 81 to 90 of about 864,970 (299)

Combinatorial Designs with Two Singular Values I. Uniform Multiplicative Designs [PDF]

open access: yes
In this and a sequel paper [10] we study combinatorial designs whose incidence matrix has two distinct singular values.These generalize 2-(v, k, É) designs, and include partial geometric designs and uniform multiplicative designs.Here we study the latter,
Spence, E., Dam, E.R. van
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Combinatorial designs and cellular automata: A survey

open access: yesDiscrete Applied Mathematics
35 pages, 8 ...
Luca Manzoni   +2 more
openaire   +4 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Combinatorial problems arising from pooling designs for dna library screening

open access: yesLe Matematiche, 2004
Colbourn (1999) developed some strategy for nonadaptive group testing when the items are linearly ordered and the positive items form a consecutive subset of all items.Müller and Jimbo (2004) improved his strategy by introducing the concept of 2 ...
Masakazu Jimbo, Meinard Müller
doaj  

The family of block designs with some combinatorial properties [PDF]

open access: yes, 1993
The family of block designs is of importance in statistical design theory because of its appealing combinatorial and statistical properties. Block designs have opened up many interesting and challenging problems in combinatorial mathematics.
Kageyama, Sanpei
core   +1 more source

A combinatorial approach to the design of vaccines

open access: yesJournal of Mathematical Biology, 2014
We present two new problems of combinatorial optimization and discuss their applications to the computational design of vaccines. In the shortest λ-superstring problem, given a family S1,...,S(k) of strings over a finite alphabet, a set Τ of "target" strings over that alphabet, and an integer λ, the task is to find a string of minimum length containing,
Martínez, Luis   +5 more
openaire   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Encryption methods based on combinatorial designs

open access: yes, 1986
We explore the use of some combinatorial designs for possible use as secret codes. We are motivated to use designs as (1) combinatorial designs are often hard to find, (2) the algorithms for encryption ond decryption are of reasonable length, (3 ...
Jennifer Seberry (19583125)   +1 more
core   +1 more source

Computational approaches to metabolic engineering utilizing systems biology and synthetic biology

open access: yesComputational and Structural Biotechnology Journal, 2014
Metabolic engineering modifies cellular function to address various biochemical applications. Underlying metabolic engineering efforts are a host of tools and knowledge that are integrated to enable successful outcomes.
Stephen S. Fong
doaj   +1 more source

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