Results 41 to 50 of about 5,218 (313)
Games of Nim with Dynamic Restrictions
The authors present formulas for the previous player’s winning positions of two variants of restricted Nim. In both of these two games, there is one pile of stones, and in the first variant, we investigate the case that in k-th turn, you can remove f(k ...
Keita Mizugaki +4 more
doaj +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Combinatorial Game Theory [PDF]
Given a combinatorial game, can we determine if there exists a strategy for a player to win the game, and can we pinpoint what this strategy is? The answer to these questions varies from game to game, and even the most trivial games can become a burden ...
Stajsic, Davorin +1 more
core
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
In the context of intelligent construction and building industrialization, assembly buildings face many challenges in quality management due to their special design and construction characteristics.
Qiao Sun +4 more
doaj +1 more source
In this paper, the dynamic spectrum access is investigated in satellite internet. Firstly, to describe the confrontation characteristics of the electromagnetic environment, two opposing teams denoted as the blue team (BT) and red team (RT), are designed.
Peijie Yan +3 more
doaj +1 more source
Remarks on strategies in combinatorial games
Viewing strategies in combinatorial games as a relation \(S\subset X\times X\) where X is the set of states (instead of a mapping \(S: X\to X)\) the authors give: 1) a very short proof of the existence of a loss-preventing strategy, 2) a proof of the existence of a winning strategy without the axiom of choice, and 3) a proof of the theorem on the value
Ales Pultr, J. Úlehla
openaire +2 more sources
MITF maintains genome stability in nonmelanocyte lineages
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
On The Foundations of Digital Games [PDF]
Computers have lead to a revolution in the games we play, and, following this, an interest for computer-based games has been sparked in research communities.
Björk, Staffan, Bj\uf6rk, Staffan
core
Playing cards: spatial arrangements for observational learning
This paper looks at how players of a card game create spatial arrangements of playing cards, and the cognitive and communicative effects of such arrangements.
Maare Åsa Harvard
doaj +1 more source

