Results 41 to 50 of about 1,365,580 (287)

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Stanley's character polynomials and coloured factorisations in the symmetric group [PDF]

, 2008
In Stanley [R.P. Stanley, Irreducible symmetric group characters of rectangular shape, Sém. Lothar. Combin. 50 (2003) B50d, 11 p.] the author introduces polynomials which help evaluate symmetric group characters and conjectures that the coefficients of ...
Rattan, Amarpreet, Rattan, A.
core   +1 more source

Subdivision of graphs in R(mK2,P4)

Heliyon, 2020
For any graphs F,G, and H, the notation F→(G,H) means that any red-blue coloring of all edges of F will contain either a red copy of G or a blue copy of H. The set R(G,H) consists of all Ramsey (G,H)-minimal graphs, namely all graphs F satisfying F→(G,H)
Kristiana Wijaya, Edy Tri Baskoro, Hilda Assiyatun, Djoko Suprijanto   +3 more
doaj   +1 more source

On the enumeration of uniquely reducible double designs [PDF]

Discrete Mathematics & Theoretical Computer Science, 2005
A double $2$-$(v,k,2 \lambda)$ design is a design which is reducible into two $2$-$(v,k,\lambda)$ designs. It is called uniquely reducible if it has, up to equivalence, only one reduction.
Veerle Fack, Svetlana Topalova, Joost Winne   +2 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Moving forward with combinatorial interaction testing [PDF]

, 2013
Combinatorial interaction testing (CIT) is an efficient and effective method of detecting failures that are caused by the interactions of various system input parameters. In this paper, we discuss CIT, point out some of the difficulties of applying it in
Demiröz, Gülşen, Porter, Adam, Fouche, Sandro, Cohen, Myra B., Yılmaz, Cemal, Koç, Uğur   +5 more
core   +1 more source

EXAMINING HIGHER ORDER THINKING IN INDONESIAN LOWER SECONDARY MATHEMATICS CLASSROOMS [PDF]

, 2020
Indonesian students’ poor performance in the mathematics test of PISA 2015 prompted the decision by the Ministry of Education of Indonesia to pay more attention to the integration of higher-order thinking (HOT) in the curricula starting in 2018. This new
Doorman, L.M., Sub Mathematics Education, Doorman, Michiel, Mathematics Education, Tanudjaya, Citra Putriarum   +4 more
core   +2 more sources

Aligned plane drawings of the generalized Delaunay-graphs for pseudo-disks

Journal of Computational Geometry, 2020
We study general Delaunay-graphs, which are natural generalizations of Delaunay triangulations to arbitrary families, in particular to pseudo-disks. We prove that for any finite pseudo-disk family and point set, there is a plane drawing of their Delaunay-
Balázs Keszegh, Dömötör Pálvölgyi
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source