Results 51 to 60 of about 1,365,580 (287)
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Digital technology in mathematics education: Why it works (or doesn't) [PDF]
, 2012 The integration of digital technology confronts teachers, educators and researchers with many questions. What is the potential of ICT for learning and teaching, and which factors are decisive in making it work in the mathematics classroom? To investigate
Drijvers, Paul +3 more
core +2 more sources
Multipartite Ramsey numbers for the union of stars
Electronic Journal of Graph Theory and Applications, 2022 Let s and k be positive integers with k ≥ 2 and G1, G2, …, Gk be simple graphs. The set multipartite Ramsey number, denoted by Ms(G1, G2, …, Gk), is the smallest positive integer c such that any k-coloring of the edges of Kc × s contains a monochromatic ...
I Wayan Palton Anuwiksa +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Machine learning‐based scheduling: a bibliometric perspective
IET Collaborative Intelligent Manufacturing, 2021 In recent years, the rapid development of artificial intelligence and data science has given rise to the study of data driven algorithms in highly volatile systems. The scheduling of complex shop floor resources falls into such a category, which is often
Shiyun Li +6 more
doaj +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Philosophia Scientiæ, 2005 Carl Friedrich Hindenburg (1741-1808), founder of the “so-called Combinatorial School” (Eugen Netto), had been forgotten until recently. However, an article about him can be found in the Dictionary of Scientific Biography.
Philippe Séguin
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau +11 more
wiley +1 more source