Results 171 to 180 of about 39,679 (279)

Combinatorial optimization methods applied to the FTTx network design problem [PDF]

, 2023
Suzianne Miranda Tormann
openalex  

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Ferroelectric compute-in-memory annealer for combinatorial optimization problems. [PDF]

Nat Commun
Yin X, Qian Y, Vardar A, Günther M, Müller F, Laleni N, Zhao Z, Jiang Z, Shi Z, Shi Y, Gong X, Zhuo C, Kämpfe T, Ni K.   +13 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Constructive Characterization Theorems in Combinatorial Optimization (Combinatorial Optimization and Discrete Algorithms)

, 2010
Erika R. Bérczi‐Kovács, László A. Végh   +1 more
openalex   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Combinatorial optimization of the hybrid cellulase complex structure designed from modular libraries. [PDF]

Sci Rep
Nakazawa H, Okada I, Ito T, Ishigaki Y, Kumagai I, Umetsu M.   +5 more
europepmc   +1 more source

Machine learning for combinatorial optimization of brace placement of steel frames [PDF]

, 2018
Takuya Tamura, Makoto Ohsaki, Jiro TAKAGI   +2 more
openalex   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Combinatorial optimization of pathway, process and media for the production of p-coumaric acid by Saccharomyces cerevisiae. [PDF]

Microb Biotechnol
Moreno-Paz S, van der Hoek R, Eliana E, Martins Dos Santos VAP, Schmitz J, Suarez-Diez M.   +5 more
europepmc   +1 more source