Results 51 to 60 of about 4,919,639 (299)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
A new efficient transformation of the generalized vehicle routing problem into the classical vehicle routing problem [PDF]
Yugoslav Journal of Operations Research, 2011 Classical combinatorial optimization problems can be generalized in a natural way by considering a related problem relative to a given partition of the nodes of the graph into node sets.
Pop Petrica, Pop-Sitar Corina
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Multicriteria combinatorial optimization problems on a set of polypermutations. [PDF]
, 2008 The studies on multicriteria combinatorial optimization are continued. A possible approach to solving multicriterion problems is developed and substantiated. An algorithm is developed and implemented.
Koliechkina, L. +3 more
core
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
On a problem in combinatorial geometry
Discrete Mathematics, 1983 AbstractLet us fix a number α ...
openaire +2 more sources
A combinatorial problem in logic
Discrete Mathematics, 1977 AbstractThis short note is an application of some theorems of graph theory to the problem of the minimum number of counter-examples needed to show that a special class of theories is complete.
Claude Berge 0001, A. Ramachandra Rao
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A combinatorial approach to the classification problem [PDF]
European Journal of Operational Research, 1999 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Yanev, N., Balev, S.
openaire +4 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Bird Mating Optimizer for Combinatorial Optimization Problems
IEEE Access, 2020 The bird mating optimizer is a new metaheuristic algorithm that was originally proposed to solve continuous optimization problems with a very promising performance.
Anas Arram +3 more
doaj +1 more source