Results 61 to 70 of about 28,946 (263)

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

On a Logical Model of Combinatorial Problems [PDF]

open access: yesOALib, 2015
The paper proposes a logical model of combinatorial problems, also it gives an example of a problem of the class NP that can not be solved in polynomial time on the dimension of the problem.
openaire   +2 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Recursive Quantum Relaxation for Combinatorial Optimization Problems [PDF]

open access: yesQuantum
Quantum optimization methods use a continuous degree-of-freedom of quantum states to heuristically solve combinatorial problems, such as the MAX-CUT problem, which can be attributed to various NP-hard combinatorial problems.
Ruho Kondo   +3 more
doaj   +1 more source

Algorithm for Solving and Updating Combinatorial Skyline [PDF]

open access: yesJisuanji gongcheng, 2017
Existing algorithms for querying combinatorial Skyline have low pruning efficiency and unsatisfactory computing speed for low-dimensional data set.Aiming at these problems,this paper proposes a fast algorithm for solving and updating combinatorial ...
DONG Leigang,LIU Guohua
doaj   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Efficient Resource Allocation in RIS-Assisted UAVs-Enabled B5G/6G Networks Using Digital Twins

open access: yesIEEE Access
Rapid technological advancements have revolutionized how people live, work, and communicate. Given the rapidly growing need for data and bandwidth, replacing existing communication systems with agile and modern alternatives is crucial.
Aasma Shafi   +2 more
doaj   +1 more source

On a Combinatorial Problem of Asmus Schmidt [PDF]

open access: yesThe Electronic Journal of Combinatorics, 2004
For any integer $r\ge2$, define a sequence of numbers $\{c_k^{(r)}\}_{k=0,1,\dots}$, independent of the parameter $n$, by $$ \sum_{k=0}^n{n\choose k}^r{n+k\choose k}^r =\sum_{k=0}^n{n\choose k}{n+k\choose k}c_k^{(r)}, \qquad n=0,1,2,\dots. $$ We prove that all the numbers $c_k^{(r)}$ are integers.
openaire   +3 more sources

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

open access: yesFEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

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