Results 101 to 110 of about 9,504,189 (270)
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Martin M. Varghese +3 more
openaire +1 more source
Stainless steels are well known to be prone to cold welding and material transfer in sliding contacts and therefore difficult to cold form unless certain precautions as discussed in this paper are taken. In the present study different combinations of tool steels/stainless steels/lubricants has been evaluated with respect to their galling resistance ...
Eriksson, Jenny, Olsson, Mikael
openaire +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Front view of a White Plainsman A4T-1600 tractor. Test #1070, 1970 The tractor is shown with a large Disc Harrow in a field.
Nebraska Tractor Test Laboratory
core
A model of friction for a pin-on-disc configuration with imposed pin rotation [PDF]
A friction model is developed by considering the Coulomb friction model, a probabilistic approach of wear prediction, the kinematics of the pin-on-disc configuration and the elastic theory of bending.
Hadfield, Mark +3 more
core +2 more sources
A Study of Metallo Beta Lactamase Producing Clinical Isolates of Pseudomonas aeruginosa
Introduction: The emergence and rapid spread of multidrug resistant Pseudomonas aeruginosa causing nosocomial infections is a great concern worldwide.
Mohite SL, Ghorpade MV
doaj
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Introduction: In recent years, considerable increase in the prevalence and multidrug resistance (MDR) in P.aeruginosa has been noticed with high morbidity and mortality.
Rakesh Kumar +5 more
doaj
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both +7 more
wiley +1 more source

