Results 101 to 110 of about 9,504,189 (270)

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Detection of MBL among Carbapenem resistant Enterobacteriaceae in a tertiary hospital using combined disc test

open access: yesInternational Journal of Current Microbiology and Applied Sciences, 2020
Martin M. Varghese   +3 more
openaire   +1 more source

Evaluation of galling resistance for some selected combinations of tool steels/stainless steel sheet materials/lubricants using pin-on-disc testing

open access: yes, 2010
Stainless steels are well known to be prone to cold welding and material transfer in sliding contacts and therefore difficult to cold form unless certain precautions as discussed in this paper are taken. In the present study different combinations of tool steels/stainless steels/lubricants has been evaluated with respect to their galling resistance ...
Eriksson, Jenny, Olsson, Mikael
openaire   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Demonstration; White

open access: yes
Front view of a White Plainsman A4T-1600 tractor. Test #1070, 1970 The tractor is shown with a large Disc Harrow in a field.
Nebraska Tractor Test Laboratory
core  

A model of friction for a pin-on-disc configuration with imposed pin rotation [PDF]

open access: yes, 2011
A friction model is developed by considering the Coulomb friction model, a probabilistic approach of wear prediction, the kinematics of the pin-on-disc configuration and the elastic theory of bending.
Hadfield, Mark   +3 more
core   +2 more sources

A Study of Metallo Beta Lactamase Producing Clinical Isolates of Pseudomonas aeruginosa

open access: yesOnline Journal of Health & Allied Sciences, 2014
Introduction: The emergence and rapid spread of multidrug resistant Pseudomonas aeruginosa causing nosocomial infections is a great concern worldwide.
Mohite SL, Ghorpade MV
doaj  

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

DETECTION AND ANTIMICROBIAL SUSCEPTIBILITY PATTERN OF PSEUDOMONAS AERUGINOSA ISOLATES IN VARIOUS CLINICAL SAMPLES WITH SPECIAL REFERENCE TO METALLO BETA LACTAMASE FROM A TERTIARY CARE HOSPITAL IN JAIPUR, INDIA

open access: yesNational Journal of Medical Research, 2014
Introduction: In recent years, considerable increase in the prevalence and multidrug resistance (MDR) in P.aeruginosa has been noticed with high morbidity and mortality.
Rakesh Kumar   +5 more
doaj  

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

open access: yesMolecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both   +7 more
wiley   +1 more source

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