Results 1 to 10 of about 8,561,310 (253)

Modified Double-Disc Synergy Test (MDDST) Versus Double-Disc Synergy Test (DDST) for Detection of ESBL(s) in AmpC β-Lactamase-Producing Klebsiella Clinical Isolates [PDF]

European Chemical Bulletin, 2018
The detection of ESBL (S) in gram-negative bacteria that produce AmpC beta-lactamases is problematic. In the present study, the performance of MDDST that employs a combination of cefepime and piperacillin-tazobactam for the detection of ESBL (S) Klebsiella producing AmpC beta-lactamases was evaluated and compared with DDST.
Atef M. Diab, M. H. Abul-Aziz, Iman M. A. El-Kholy, Mona A. Rezk   +3 more
exaly   +9 more sources

Comparison of Combined Disc Synergy Test and Double Disc Synergy Test for Phenotypic Detection of Metallo-ß-Lactamase Among the Clinical Isolates of Gram-Negative Bacilli [PDF]

International Journal of Research in Medical Sciences, 2022
Background: Metallo-β-lactamases (MBL) have a wide spectrum of activity and they confer a higher level of resistance to all β-lactams antibiotics including Carbapenem. The active site in MBLs contains either 1 or 2 Zn2+ ions for their catalytic mechanism. All MBLs share a common feature of being inhibited by EDTA.
Rifat Asma Chowdhury, Sabrina Sharmin, Abu Hena Md. Saiful Karim Chowdhury, Nasima Akter, Shakeel Ahmed, Gulshan Nigar Choudhury   +5 more
exaly   +3 more sources

Comparison of Double-Disc Synergy, Combined Disc Diffusion, and E Test for Metallo-Beta-Lactamase Detection in Pseudomonas aeruginosa in a Tertiary Care Hospital

Asian Journal of Pharmaceutical and Clinical Research, 2023
Objective: Pseudomonas aeruginosa is an important opportunistic pathogen associated with nosocomial infections. The metallo-beta-lactamases (MBLs) are an important class of carbapenemases which are predominantly produced by P. aeruginosa. This study is aimed to study the prevalence of MBLs among imipenem (IMP)-resistant P.
Varshini D, Anu priya A, LAITHAMBIGAI J, Chitra Rajalakshmi P, Saraswathi R   +4 more
exaly   +4 more sources

A comparative study of VITEK-2, Double Disc Synergy and Combined Disc Methods for detection of ESBL (Extended Spectrum Beta-Lactamase) production in Escherichia coli and Klebsiella pneumoniae strains

Journal of Contemporary Medicine, 2022
Aim: In this prospective study we aimed to compare the effectiveness of VITEK-2 (bioMérieux, France) automated system, double-disc synergy (DDST) versus combined disc test (CDT) in detecting the Extended-Spectrum Beta-Lactamase (ESBL) positivity in ...
Mustafa Yılmaz, Öznur Ak, Demet Hacıseyitoğlu, Sevil Alkan   +3 more
doaj   +4 more sources

Abattoirs as Non-Hospital Source of Extended Spectrum Beta Lactamase Producers: Confirmed by the Double Disc Synergy Test and Characterized by Matrix-Assisted Laser Desorption/Ionization Time of Flight Mass Spectrometry [PDF]

PLoS ONE, 2014
In this study, the presence of extended spectrum beta lactamase (ESBL) producing organisms in abattoirs, a non-hospital community was investigated. The presence of ESBL-producing phenotypes was confirmed by the Double Disc Synergy Test (DDST). Out of the 99 isolates screened for ESBL, 28 (28.3%) were confirmed positive.
Moses Nkechukwu Ikegbunam, Linda Onyeka Anagu, Ifeanyi R Iroha, Chika Ebiye Ejikeugwu, Charles Okey Esimone   +4 more
europepmc   +7 more sources

Kinetics activity of Yersinia Intermedia Against ZnO Nanoparticles Either Synergism Antibiotics by Double-Disc Synergy Test Method [PDF]

Iranian Journal of Biotechnology, 2016
Bacterial resistance to the commonly used antibacterial agents is an increasing challenge in the medicine, and a major problem for the health care systems; the control of their spread is a constant challenge for the hospitals.In this study, we have investigated the antimicrobial activity of the Zinc Oxide nanoparticles against clinical sample; Yersinia
Motahareh, Fathi Azar Khavarani, Mahla, Najafi, Zahra, Shakibapour, Davood, Zaeifi   +3 more
openaire   +3 more sources

Comparison of Three Dimensional Test and Double Disc Synergy Test for Detection of Extended Spectrum ?-Lactamase (ESBL) Producing Gram Negative Bacteria

Pulse, 2014
Extended spectrum ?-lactamase (ESBLs), produced by Gram negative organisms, are enzymes capable of hydrolyzing extended spectrum cephalosporins, penicillins and monobactam but inactive against cephamycin and imipenem. Detection of some ESBL strains are missed by Double disc synergy test but detected by three dimensional test.
Ta Nasir
exaly   +3 more sources

Phenotypic Cofirmatory Disc Diffusion Test (PCDDT), Double Disc Synergy Test (DDST), E-Test OS Diagnostic Tool for Detection of Extended Spectrum Beta Lactamase (ESΒL) Producing Uropathogens [PDF]

Journal of Applied Biotechnology & Bioengineering, 2017
Background The aim of this study was to probe the best diagnostic tool for the detection of Extended Spectrum beta lactamase ES beta L producing uropathogen and their antimicrobial susceptibility profile to treat the infections properly Methods Clinical samples of urine were cultured on Cysteine Lactose Electrolyte Deficient CLED Agar ...
exaly   +2 more sources

Detection of O25B-ST131 clone and blaCTX-M-15 gene in Escherichia coli isolated from patients with COVID-19 [PDF]

PeerJ
Background Isolation of blaCTX-M family of extended-spectrum beta-lactamases (ESBL) is a challenge in the field of microbiology in our locality that makes treatment fail and disseminate quickly.
Khanda Abdulateef Anwar
doaj   +3 more sources

Molecular detection of CTX-M gene from ducks sold in traditional markets in Surabaya, Indonesia [PDF]

Open Veterinary Journal
Background: Extended-spectrum β-lactamases (ESBLs), particularly those encoded by the cefotaxime (CTX-M) gene family, represent a significant threat to antimicrobial resistance. Ducks sold in traditional markets have been identified as active reservoirs
Wiwiek Tyasningsih, Mustofa Helmi Effendi, Aswin Rafif Khairullah, Budiastuti Budiastuti, Freshinta Jellia Wibisono, Irfan Alias Kendek, Mariana Febrilianti Resilinda, Saifur Rehman, Ikechukwu Benjamin Moses, Sheila Marty Yanestria   +9 more
doaj   +2 more sources