Results 71 to 80 of about 971,475 (405)

Composite local low-rank structure in learning drug sensitivity [PDF]

CIBB 2019,http://www.cibb2019.it/, 2019
The molecular characterization of tumor samples by multiple omics data sets of different types or modalities (e.g. gene expression, mutation, CpG methylation) has become an invaluable source of information for assessing the expected performance of individual drugs and their combinations.
arxiv   +1 more source

High Resolution In Vivo Bioluminescent Imaging for the Study of Bacterial Tumour Targeting [PDF]

, 2012
The ability to track microbes in real time in vivo is of enormous value for preclinical investigations in infectious disease or gene therapy research. Bacteria present an attractive class of vector for cancer therapy, possessing a natural ability to grow
A Briat, A-L Puaux, AE Spinelli, AJ Chaudhari, Ali R. Akin, BJ Bachmann, BJ Beattie, C Clairmont, C Cunningham, C Grillot-Courvalin, C Kuo, C Nagakura, CH Contag, Chwanrow K. Baban, CK Baban, CM Cheng, Cormac G. Gahan, CU Riedel, CU Riedel, D Kepshire, D Morrissey, Douwe van Sinderen, Efstathios Karathanasis, F Heppner, G Vassaux, Gerald C. O'Sullivan, Gooitzen M. van Dam, J Nemunaitis, Jae-Beom Kim, Jeff Meganck, JF Toso, JJ Min, JP van Pijkeren, K Hayashi, K Hayashi, K Yazawa, Kevin P. Francis, M Cronin, M Cronin, M Cronin, M Tangney, M Zhao, M Zhao, M Zhao, Mark Tangney, Michelle Cronin, MJ Lemmon, ML Foucault, ML Foucault, MS Waidmann, N Andreu, NC Shaner, Ning Zhang, Noriyuki Kasahara, P Alvarez-Martin, PJ Simpson, R Belas, RD Sleator, RJ Critchley, RM Hoffman, RM Hoffman, S Ahmad, S Ahmad, S Guglielmetti, S Wiles, Sara A. Collins, SK Hoiseth, SM Burns-Guydish, Susan A. Joyce, U Iqbal, X Guo, YA Yu, YA Yu   +72 more
core   +6 more sources

Adenosquamous Carcinoma of Extrahepatic Bile Duct: A Case Report [PDF]

, 2007
Most malignant tumors originating from the biliary tract are adenocarcinomas, and adenosqamous carcinoma of Klatskin's tumor is a very rare finding. An 83-yr-old man was admitted to our hospital because of jaundice.
Anna Kim, Chen, Gonzalez Gonzalez, Gu, Hayashi, Hoon Go, Hyeon Woong Yang, Iemura, Lantsberg, Leung, Ochiai, Okabayashi, Sang Woo Cha, Shin, Sin Hyung Lim, Song, Sung Hee Jung, Takamura, Vallis, Woong Chul Lee   +19 more
core   +2 more sources

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

Molecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi, Janelle‐Cheri Millen, Romela Irene Ramos, Jennifer A. Linehan, Timothy G. Wilson, Dave S. B. Hoon, Matias A. Bustos   +6 more
wiley   +1 more source

A Markov decision process approach to optimizing cancer therapy using multiple modalities [PDF]

, 2017
There are several different modalities, e.g., surgery, chemotherapy, and radiotherapy, that are currently used to treat cancer. It is common practice to use a combination of these modalities to maximize clinical outcomes, which are often measured by a balance between maximizing tumor damage and minimizing normal tissue side effects due to treatment ...
arxiv   +1 more source

Preoperative Prognosis Assessment of Lumbar Spinal Surgery for Low Back Pain and Sciatica Patients based on Multimodalities and Multimodal Learning [PDF]

arXiv, 2023
Low back pain (LBP) and sciatica may require surgical therapy when they are symptomatic of severe pain. However, there is no effective measures to evaluate the surgical outcomes in advance. This work combined elements of Eastern medicine and machine learning, and developed a preoperative assessment tool to predict the prognosis of lumbar spinal surgery
arxiv  

Combined modality therapy versus chemotherapy alone as an induction regimen for primary central nervous system lymphoma: a decision analysis

British Journal of Haematology, 2012
In immunocompetent patients with primary central nervous system (CNS) lymphoma, combined modality therapy (CMT) using high‐dose methotrexate and whole brain radiotherapy has improved response rates compared to chemotherapy alone. The trade‐off is delayed
A. Prica, Kelvin K. W. Chan, M. Cheung
semanticscholar   +1 more source

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

Molecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran, Clarence Yapp, Gregory J. Baker, Johanna Beyer, Young Hwan Chang, Allison L. Creason, Robert Krueger, Jeremy Muhlich, Nathan Heath Patterson, Kevin Sidak, Damir Sudar, Adam J. Taylor, Luke Ternes, Jakob Troidl, Xie Yubin, Artem Sokolov, Darren R. Tyson   +16 more
wiley   +1 more source

Clinical Analysis of 45 Patients with Thymic Carcinoma

Cancer Biology & Medicine, 2009
OBJECTIVE To retrospectively evaluate the prognostic factors for advanced thymic carcinoma. METHODS The data from 45 patients with advanced thymic carcinoma were retrospectively analyzed according to Masaoka stage criteria.
Ruitai FAN, Jingmin WANG, Hongzhi ZHANG
doaj   +1 more source

Primary endocrine therapy of locally advanced breast cancer patients [PDF]

Archive of Oncology, 2003
Primary endocrine therapy has been traditionally reserved for elderly and unfit locally advanced breast cancer patients (LABC patients). In this group, the primary endocrine therapy could not be adequately compared to primary chemotherapy.
Nešković-Konstantinović Zora B.
doaj   +1 more source