Results 111 to 120 of about 9,967,589 (303)

Pegademase bovine (PEG-ADA) for the treatment of infants and children with severe combined immunodeficiency (SCID) [PDF]

open access: yes, 2009
Adenosine deaminase deficiency (ADA) is a rare, inherited disorder of purine metabolism characterized by immunodeficiency, failure to thrive and metabolic abnormalities. A lack of the enzyme ADA allows accumulation of toxic metabolites causing defects of
Claire Booth   +3 more
core  

Patient demographics, tumor characteristics, and treatment modality.

open access: yes, 2016
Patient demographics, tumor characteristics, and treatment modality.
Maoli Duan (453289)   +8 more
core   +1 more source

Integration of Serum Neurofilament Light Chain and Cortical Dysfunction Improves Diagnostic Accuracy in ALS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether integration of serum neurofilament light chain (NfL) and cortical dysfunction improves diagnostic accuracy in amyotrophic lateral sclerosis (ALS) when applied alongside the Gold Coast criteria (GCC). Methods In this prospective study, 148 participants with suspected ALS were recruited (101 ALS and 47 with ALS ...
Aicee Dawn Calma   +16 more
wiley   +1 more source

Treatment of objective: necessity-modality approach.

open access: yes, 2014
Treatment of objective: necessity-modality approach.
Dayi He (618299)   +3 more
core   +1 more source

A case of pathological complete regression in combined modality treatment of resectable Her2/neu-positive gastric cancer

open access: yesСибирский онкологический журнал
Background. Overexpression of Her2neu occurs in 15–20% of patients with gastric cancer and correlates with an unfavorable prognosis. Case report.
A. V. Avgustinovich   +7 more
doaj   +1 more source

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin   +8 more
wiley   +1 more source

Effect of combined modality treatment on morphofunctional state of bronchial epithelium in lung cancer patients

open access: yesСибирский онкологический журнал, 2016
Effect of combined modality treatment on morphofunctional state of the bronchial epithelium of 29 patients with stage III lung cancer was studied. Neoadjuvant chemotherapy (paclitaxel/carboplatin) had no negative effect on the state of the bronchial ...
A. Yu. Dobrodeev   +4 more
doaj  

Long‐Term Neurologic Exam Findings in People Diagnosed and Treated During Acute HIV Infection

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Evaluate clinical and laboratory correlates of abnormal neurologic exam findings after acute HIV infection (AHI). Methods Participants from the RV254/SEARCH 010 cohort in Bangkok underwent standardized neurologic examinations at Weeks 0 (AHI), 12, 96, and 288 following antiretroviral therapy (ART).
Kathryn B. Holroyd   +118 more
wiley   +1 more source

Combined treatment modalities in wet AMD

open access: yesMedical & Clinical Research, 2020
Introduction: АМD is a disease of social significance and an increasing incidence. The patients with wet AMD need a life-long treatment in order to sustain useful vision. The Anti-VEGF treatment does not ameliorate the dry component of the disease. That’s why an alternative treatment is highly needed.
openaire   +1 more source

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