Results 71 to 80 of about 3,821,748 (294)

Genotype–Phenotype Correlations of Monoallelic PFIC Variants in Pediatric Liver Disease: A Multicenter Retrospective Cohort Study

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Progressive familial intrahepatic cholestasis (PFIC) is classically caused by biallelic pathogenic variants, yet monoallelic variants of uncertain significance (VUS) in PFIC‐associated genes are increasingly identified in children with cholestasis, creating diagnostic uncertainty.
Brett J. Hoskins, Tiziano Pramparo, Chaowapong Jarasvaraparn, Michael J. Wilsey, Voytek Slowik, Lakshmi Kunam, Janis M. Stoll, Ruben E. Quiros‐Tejeira, Simon Lam, Wikrom Karnsakul   +9 more
wiley   +1 more source

Combined oral contraceptive utilization and uterine fibroid incidence: A prospective study in a cohort of African-American women.

PLoS ONE
Published associations between combined oral contraceptive use and uterine fibroid development have lacked prospective imaging with ultrasound to distinguish between incident and prevalent fibroids.
Sarah R Hoffman, Jennifer S Smith, Michele Jonsson Funk, Michael G Hudgens, Charles Poole, Wanda K Nicholson, Donna D Baird, Quaker E Harmon   +7 more
doaj   +1 more source

ADNP‐Related Helsmoortel–Van der Aa Syndrome: A Review of the Literature and Clinical Recommendations for Assessment and Monitoring

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT ADNP‐related Helsmoortel–Van der Aa syndrome (ADNP‐related HVDAS) is a single gene form of autism spectrum disorder (ASD) caused by pathogenic sequence variants in the activity‐dependent neuroprotective protein (ADNP) gene. In addition to ASD, ADNP‐related HVDAS is associated with a wide range of cognitive, behavioral, and physical health ...
Jarrett Fastman, Ana Kolevzon, Paige Siper, Tess Levy, Jeffrey M. Saland, Yitzchak Frank, Robert Rapaport, Kayla Kupietzky, William E. Bennett Jr, Bruce Gelb, Sandra Bedrosian Sermone, Alexander Kolevzon   +11 more
wiley   +1 more source

Bone Mineral Density Among Long-term Users of Hormonal Contraception (Contraception and Bone Mineral Density) [PDF]

Al-Azhar International Medical Journal
Background: Hormonal contraceptives that involve steroids have a high success rate and are commonly used. The use of these contraceptives can have positive and negative effects on health, including bone health.
Hanaa Abd El Hameed El Ebeisy, Nahed Ezzat Mahmoud, Hanaa Taha Kandeel, Shaimaa Mahmoud Saad El Tawwab   +3 more
doaj   +1 more source

Health consequences of combined oral contraceptives [PDF]

British Medical Bulletin, 2000
During the past 40 years, combined oral contraceptives (COCs) have become a key component of modern fertility regulation programmes. Today, an estimated 100 million women throughout the world use this method of contraception. With such wide-spread usage, it is perhaps not surprising that COCs have been the subject of extensive medical research.
openaire   +2 more sources

Pharmacology and Drug Interactions of Hormonal Contraceptives

, 2022
Hormonal Contraceptives come in various types and delivery systems. Short-acting reversible contraceptives have oral, injectable, transdermal skin patch and intravaginal ring preparations.
Kuwanda, Tendaishe Monalissa
core  

Rethinking brachycephaly: Anatomical implications and health considerations in lagomorphs

The Anatomical Record, EarlyView.
Abstract Brachycephaly in domestic rabbits is increasingly perceived by welfare organizations as associated with significant health complications, particularly oral pathologies. Despite this perception, comparative anatomical research into rabbit brachycephaly is limited compared to that of dogs and cats, compelling an in‐depth examination of its ...
Helaina Cressy, Alice Nishigaki, Matthew C. Gage, Renato L. Previdelli   +3 more
wiley   +1 more source

Peak Serum Vancomycin Levels Are Achieved Between 6 and 24 Hours After Implantation of Vancomycin‐Soaked Anterior Cruciate Ligament Grafts

Arthroscopy, EarlyView.
Purpose To examine systemic exposure and elution characteristics of liquid vancomycin‐soaked anterior cruciate ligament (ACL) grafts in vivo by assessing serum vancomycin levels over 48 hours after ACL reconstruction and comparing the resulting concentrations with the toxic threshold of 15 to 20 μg/mL.
Swen Witteveen, Steffen T. Ubl, Sophia Krombholz, Daniel Guenther, Carolin Flieser, Arasch Wafaisade, Bertil Bouillon, Mario Thevis, Thomas R. Pfeiffer   +8 more
wiley   +1 more source

Use of Clotrimazole in Finfish Aquaculture: Mechanistic Insights, Limitations, and Future Directions for Antifungal Therapy

Animal Research and One Health, EarlyView.
This review critically evaluates clotrimazole as a potential antifungal for finfish aquaculture, highlighting strong mechanistic and in vitro efficacy against aquatic mycoses alongside major gaps in in vivo evidence, toxicokinetics, residue safety, and environmental risk, outlining priorities for responsible therapeutic development and regulatory ...
Arya Sen, Debashri Mondal, Thangapalam Jawahar Abraham   +2 more
wiley   +1 more source

Postabortal rehabilitation: theoretical and practical aspects

Медицинский совет, 2014
The need for post-abortion rehabilitation is conditioned by the frequency and relevance of delayed and long-term complications of induced abortions. Numerous studies demonstrate feasibility of using oral contraceptives for the prevention of adverse ...
A. L. Unanyan, S. E. Arakelov, L. S. Polonskaya, T. D. Guriyev, V. A. Alimov, D. V. Baburin, A. E. Kadyrova, Y. M. Kossovich   +7 more
doaj   +1 more source