Results 141 to 150 of about 26,843 (264)

Secondary Pituitary Hyperplasia: The Long-Term Consequences of Untreated Primary Hormonal Deficiencies

Endocrinology Research and Practice
Pituitary hyperplasia is an enlargement of the pituitary gland resulting from increased cell number. In contrast to adenomas, which are nodular and monoclonal, hyperplasia is a polyclonal process that may manifest in diffuse, focal, or nodular forms ...
Valentina Gasco, Daniela Cuboni, Nunzia Prencipe, Alessandro Maria Berton, Fabio Bioletto, Ezio Ghigo, Silvia Grottoli   +6 more
doaj   +1 more source

Molecular analysis of novel PROP1 mutations associated with combined pituitary hormone deficiency (CPHD)

, 2009
Mutations in PROP1 are a frequent cause of familial CPHD. We have described four novel mutations in PROP1 in 3 pedigrees, all resulting in PROP1 deficiency by different mechanisms.
Dattani, M.T., Otonkoski, T., Rhodes, S.J., Al-Khawari, M., Woods-Townsend, Kathryn, Kelberman, D., Turton, J.P.G., Greening, J., Mehta, A., Swift, P.G F.   +9 more
core   +1 more source

Proteomic and metabolic signatures of female reproductive factors and risk of age‐related ocular diseases: A large prospective cohort study

VIEW, EarlyView.
The full editable vector source file of this graphical abstract is uploaded as a supplementary EPS file for typesetting. All elements are copyright‐free. Abstract Age‐related ocular diseases (ARODs), including cataract, primary open‐angle glaucoma (POAG), and age‐related macular degeneration (AMD), are leading causes of vision impairment and exhibit ...
Linge Jian, Zhiqian Huang, Keke Zhang, Jing Lin, Jia You, Yi Lu, Xiangjia Zhu   +6 more
wiley   +1 more source

Assessing physiological, behavioral and movement responses to Suprelorin implant delivery methods in free‐ranging eastern grey kangaroos Macropus giganteus

Wildlife Biology, EarlyView.
Overabundant populations of eastern grey kangaroos Macropus giganteus in peri‐urban areas pose ecological and social challenges. Current management strategies are often hindered by animal welfare and logistical concerns. This study aimed to assess stress responses of kangaroos to two contraceptive delivery methods.
Fabiola R. O. Silva, Sebastien Comte, Tamara Keeley, Maquel Brandimarti, Catherine A. Herbert   +4 more
wiley   +1 more source

Mutational analysis of DAX1 in patients with hypogonadotropic hypogonadism or pubertal delay

, 1999
Although delayed puberty is relatively common and often familial, its molecular and pathophysiologic basis is poorly understood. In contrast, the molecular mechanisms underlying some forms of hypogonadotropic hypogonadism (HH) are clearer, following the ...
Meeks, JJ, Seminara, SB, Habiby, RL, Bick, DP, Kotlar, TJ, Gu, WX, Hindmarsh, PC, Achermann, JC, Crowley, WF, Sabacan, LP, Sherins, RJ, Layman, LC, Jameson, JL   +12 more
core  

Quantification of steroid hormones in free‐ranging Apennine wolf Canis lupus italicus hair samples collected post‐mortem

Wildlife Biology, EarlyView.
After decades of dramatic reductions in their populations, Italian wolves have begun recolonizing parts of their historic range. This growth in populations can lead to potential conflicts with human activities, which remain the main cause of wolf mortality.
Ilaria Troisio, Carmela Musto, Nicola Acquisti Casi, Nadia Govoni, Giuseppe Merialdi, Domenico Ventrella, Alberto Elmi, Mauro Delogu, Maria Laura Bacci   +8 more
wiley   +1 more source

Using programmable infusion pump in avian species – a validation methodology in geese

Wildlife Biology, EarlyView.
Wildlife face anthropogenic and natural stressors that affect their physiology and behaviour. The activity of the hypothalamic–pituitary–adrenal axis and glucocorticoid (GC) production is intrinsically linked with energy regulation and environmental stressors.
Myriam Trottier‐Paquet, Maude Gauthier‐Bouchard, Akiko Kato, Charline Parenteau, Frédéric Angelier, Pierre Legagneux   +5 more
wiley   +1 more source

Cumulative heatwave stress disrupts thermal homeostasis and plumage structure in a Mediterranean passerine

Functional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Heatwaves are becoming increasingly frequent across the Mediterranean and pose critical challenges for small passerines, yet the physiological and morphological limits to their resilience remain poorly understood.
Erick González‐Medina, Núria Playà‐Montmany, Julián Cabello‐Vergel, Marta Precioso, Deseada Parejo, Auxiliadora Villegas, José A. Masero   +6 more
wiley   +1 more source

Advent of NK3R Antagonists for the Treatment of Menopausal Hot Flushes: A Narrative Review

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT The menopause transition is marked by symptoms predominantly attributed to declining oestrogen levels. Approximately 80% of women experience associated symptoms, and 25% experience severe symptoms. The commonest are vasomotor symptoms (VMS), collectively referring to hot flushes and/or night sweats.
Aaran H. Patel, Aureliane Pierret, Edouard G. Mills, Alexander N. Comninos, Waljit S. Dhillo, Ali Abbara   +5 more
wiley   +1 more source

Frequency of mutations in PROP-1 gene in Turkish children with combined pituitary hormone deficiency

The Turkish Journal of Pediatrics, 2012
Mutations in the prophet of Pit-1 (PROP-1) gene are responsible for most of the cases of combined pituitary hormone deficiencies (CPHD). We performed this study to determine the prevalence of PROP-1 mutations in a group of Turkish children with ...
Nurgün Kandemir, Doğuş Vurallı, Ekim Taşkıran, Nazlı Gönç, Alev Özön, Ayfer Alikaşifoğlu, Engin Yılmaz   +6 more
doaj