Results 1 to 10 of about 2,654,404 (268)

Mapping intellectual structure and research hotspots in the field of fibroblast-associated DFUs: a bibliometric analysis

open access: yesFrontiers in Endocrinology, 2023
BackgroundDiabetic foot ulcers (DFUs) are one of the most popular and severe complications of diabetes. The persistent non-healing of DFUs may eventually contribute to severe complications such as amputation, which presents patients with significant ...
Yushu Zhu   +34 more
doaj   +1 more source

Chemically programmed STING-activating nano-liposomal vesicles improve anticancer immunity

open access: yesNature Communications, 2023
The often immune-suppressive tumor microenvironment (TME) may hinder immune evasion and response to checkpoint blockade therapies. Pharmacological activation of the STING pathway does create an immunologically hot TME, however, systemic delivery might ...
Xiaona Chen   +5 more
doaj   +1 more source

Tumor Immune Microenvironment Characterization in Hepatocellular Carcinoma Identifies Four Prognostic and Immunotherapeutically Relevant Subclasses

open access: yesFrontiers in Oncology, 2021
PurposeThe tumor microenvironment (TME) plays a critical role in the pathogenesis of hepatocellular carcinoma (HCC). However, underlying compositions and functions that drive the establishment and maintenance of the TME classifications are less-well ...
Xingxing Gao   +20 more
doaj   +1 more source

Emerging Roles of Liquid–Liquid Phase Separation in Cancer: From Protein Aggregation to Immune-Associated Signaling

open access: yesFrontiers in Cell and Developmental Biology, 2021
Liquid–liquid Phase Separation (LLPS) of proteins and nucleic acids has emerged as a new paradigm in the study of cellular activities. It drives the formation of liquid-like condensates containing biomolecules in the absence of membrane structures in ...
Jiahua Lu   +27 more
doaj   +1 more source

A bibliometric analysis of the role of microbiota in trauma

open access: yesFrontiers in Microbiology, 2023
IntroductionOver the last several decades, the gut microbiota has been implicated in the formation and stabilization of health, as well as the development of disease. With basic and clinical experiments, scholars are gradually understanding the important
Runzhi Huang   +28 more
doaj   +1 more source

Prevalence and predictors of scar contracture-associated re-hospitalisation among burn inpatients in China

open access: yesScientific Reports, 2021
Scar contracture, a common destructive complication causing increased re-hospitalisation rate of burn survivors and aggravated burden on the medical system, may be more seriously in Chinese population because of their higher susceptibility to scar ...
Zhe Zhu   +8 more
doaj   +1 more source

Tracing the evolving dynamics and research hotspots of microbiota and immune microenvironment from the past to the new era

open access: yesMicrobiology Spectrum, 2023
Gut microbiota can regulate many physiological processes within gastrointestinal tract and other distal sites. Dysbiosis may not only influence chronic diseases like the inflammatory bowel disease (IBD), metabolic disease, tumor and its therapeutic ...
Runzhi Huang   +20 more
doaj   +1 more source

The Progress in the Treatment of Hepatocellular Carcinoma With Portal Vein Tumor Thrombus

open access: yesFrontiers in Oncology, 2021
Hepatocellular carcinoma (HCC) is one of most prevalent cancer and is a serious healthcare issue worldwide. Portal vein tumor thrombus (PVTT) is a frequent complication and remains as the blockage in the treatment of HCC with high recurrence rate and ...
Fangzhou Luo   +18 more
doaj   +1 more source

Conventional Two-Stage Hepatectomy or Associating Liver Partitioning and Portal Vein Ligation for Staged Hepatectomy for Colorectal Liver Metastases? A Systematic Review and Meta-Analysis

open access: yesFrontiers in Oncology, 2020
Background: Pushing the surgical limits for initially unresectable colorectal liver metastases (CRLM) are two approaches for sequential liver resection: two-stage hepatectomy (TSH) and associating liver partitioning and portal vein ligation for staged ...
Liang Zhang   +9 more
doaj   +1 more source

Ultrasmall organosilica nanoparticles with strong solid-state fluorescence for multifunctional applications

open access: yesJournal of Advanced Research, 2023
Introduction: Organosilica nanoparticles (ONs), which are a new type of photoluminescent nanomaterial (PM) with excellent biocompatibility, have caught more attention in recent years.
Jianqin Wan   +4 more
doaj   +1 more source

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