Results 21 to 30 of about 2,654,404 (268)

Synergistic effect of 17-allylamino-17-demethoxygeldanamycin with dehydroxymethylepoxyquinomicin on the human anaplastic thyroid carcinoma cell line KTC2 [PDF]

open access: yesArchives of Biological Sciences, 2021
The use of targeted inhibitors has shown promise as an effective approach in cancer therapy. However, targeted therapies based only on one drug, such as 17-allylamino-17-demethoxygeldanamycin (17-AAG), have limited success, partly because cancer cells ...
Todorović Lidija   +6 more
doaj   +1 more source

A CASE REPORT OF SUCCESSFUL TREATMENT OF STAGE IV EWING’S SARCOMA IN AN ADOLESCENT PATIENT

open access: yesСибирский онкологический журнал, 2020
Background. Ewing’s sarcoma is one of the most common musculoskeletal cancers in children and adolescents. Extremely aggressive clinical course of Ewing’s sarcoma makes a successful treatment of this tumor difficult.
O. I. Kit   +12 more
doaj   +1 more source

Curcumin and Its Analogs in Non-Small Cell Lung Cancer Treatment: Challenges and Expectations

open access: yesBiomolecules, 2022
Researchers have made crucial advances in understanding the pathogenesis and therapeutics of non-small cell lung cancer (NSCLC), improving our understanding of lung tumor biology and progression.
Chunyin Tang   +9 more
doaj   +1 more source

Survival of retinoblastoma patients: a cohort study by two Russian medical centers

open access: yesРоссийский офтальмологический журнал, 2021
Purpose. To evaluate the overall, disease-specific, event-free, relapse-free survival of retinoblastoma (RB) patients and cumulative probability of eye survival in such patients.Material and methods.
S. V. Saakyan   +6 more
doaj   +1 more source

Sequential or Combined Treatment? That is the Question [PDF]

open access: yesRadiology, 2014
n ...
Iezzi, Roberto   +3 more
openaire   +2 more sources

Combination of Modified Atmosphere and Irradiation for the Phytosanitary Disinfestation of Trogoderma granarium Everts (Coleoptera: Dermestidae)

open access: yesInsects, 2021
The khapra beetle, Trogoderma granarium Everts, is defined as one of the most important quarantine pests globally, and fumigation with methyl bromide, an ozone-depleting substance, is a common phytosanitary measure currently used. The modified atmosphere
Qing-Ying Zhao   +7 more
doaj   +1 more source

Mapping intellectual structures and research hotspots of chronic wound in global perspective

open access: yesRegenerative Therapy
Background: Chronic wounds included but were not limited to diabetes foot ulcers, venous leg ulcers and pressure ulcers. The challenge of difficult healing placed a heavy burden on patients and society. Our objective was to explain the healing process of
Yushu Zhu   +21 more
doaj   +1 more source

A combination therapy of ingredients from TCM for the prevention and treatment of gastric cancer by targeting HER2/ PD-L1

open access: yesPharmacological Research - Modern Chinese Medicine, 2021
Gastric cancer (GC) is a globally important disease. Targeted therapies licensed to treat gastric cancer include trastuzumab, which targets HER2, and nivolumab or pembrolizumab, which block PD-1/PD-L1.
Ling Li   +9 more
doaj   +1 more source

Combinations of drugs in the Treatment of Obesity [PDF]

open access: yesPharmaceuticals, 2010
Obesity is a chronic disease associated with excess morbidity and mortality. Clinical treatment, however, currently offers disappointing results, with very high rates of weight loss failure or weight regain cycles, and only two drugs (orlistat and sibutramine) approved for long-term use.
Halpern, Bruno   +6 more
openaire   +3 more sources

Mitochondrial rewiring with small-molecule drug-free nanoassemblies unleashes anticancer immunity

open access: yesNature Communications
The immunosuppressive tumor microenvironment (TME) remains a major obstacle to tumor control and causes suboptimal responses to immune checkpoint blockade (ICB) therapy. Thus, developing feasible therapeutic strategies that trigger inflammatory responses
Lulu Ren   +8 more
doaj   +1 more source

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