Results 121 to 130 of about 740,350 (265)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Integrating combining ability and multivariate analysis for the selection of superior tomato hybrids. [PDF]

Front Plant Sci
Mendes TKC, Araújo MS, Silva WMB, Oliveira FAS, Bueno DAS, Lima AM, Nunes JVM, Santos JEF, Bhering LL, Silva DJH.   +9 more
europepmc   +1 more source

Frequency of heterotic hybrids in relation to general combining ability of parents in sweet corn. [PDF]

PeerJ, 2023
Madhunapantula VP, Talekar SC, Kachapur RM, Salakinkop SR, Lal M, Naidu G.   +5 more
europepmc   +1 more source

Non-additive combining abilities [PDF]

Heredity, 1964
Neil Gilbert, J L Jinks
openaire   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Dissecting heterosis and combining ability for yield and TYLCV resistance in tomato under field conditions. [PDF]

BMC Plant Biol
Hatamifard M, Lotfi M, Ramshini H.
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Combining ability and molecular marker approach for developing early maturing high yielding hybrid rice. [PDF]

Sci Rep
Shamsuddoha M, Siddika A, Kamal ASMM, Mohiuddin SJ, Rashid M-, Latif MA, Haque MA.   +6 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Combining Ability in Maize Breeding Programs in Sub-Saharan Africa: A Systematic Review. [PDF]

Genes (Basel)
Oladiran KP, Chauque PS, Chiulele RM, Gbaruko GC, Lhamine CF, Nanyangwe S, Chebichii MK, Kambani ML.   +7 more
europepmc   +1 more source