Results 131 to 140 of about 2,441,843 (293)

Evaluating Maize Hybrids for Yield, Stress Tolerance, and Carotenoid Content: Insights into Breeding for Climate Resilience

Plants
To ensure food and feed security, modern maize hybrids must not only perform well under changing climate conditions but also consistently achieve higher and stable yields, exhibit maximum tolerance to stress factors, and produce high quality grains. In a
Călin Popa, Roxana Elena Călugăr, Andrei Varga, Edward Muntean, Ioan Băcilă, Carmen Daniela Vana, Ionuț Racz, Nicolae Tritean, Ioana Virginia Berindean, Andreea D. Ona, Leon Muntean   +10 more
doaj   +1 more source

Combining ability in bhindi [ Abelmoschus spp.]

Electronic Journal of Plant Breeding, 2009
Combining ability was estimated for six diverse okra genotypes or varieties by diallel analysis. The combininganalysis revealed that Arka Anamika was found to be a good general combiner for fruit number, fruit weight and fruit length.KL9 showed high gca for days to first flowering, internode number and fruit weight.
Divya Balakrishnan, E. Sreenivasan, R. Sujatha, K. V. Suresh Babu   +3 more
openaire   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Evaluation of combining ability and genetic analysis for salinity tolerance in a 7 × 7 F1 half-diallel population of groundnut (Arachis hypogaea L.)

Discover Plants
A study was conducted at the net house of Sher-e-Bangla Agricultural University in Dhaka to develop salt-tolerant and high-yielding groundnut genotypes.
Md. Akram Hossain Chowdhury, Md. Shahidur Rashid Bhuiyan, Md. Shah-E-Alam, Md. Sarowar Hossain, Md. Fazlul Karim, Shahanaz Parveen, Md. Harun-Ur-Rashid   +6 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Assessment of combining ability for grain yield and its attributing traits in maize (Zea mays L.)

Discover Agriculture
A comprehensive understanding of combining ability is an emerging focus in hybrid maize research in Nepal. The present study aimed to evaluate the performance of single-cross maize hybrids and to estimate the combining abilities of parental lines for ...
Jiban Shrestha, Surya Kant Ghimire, Krishna Hari Dhakal, Mahendra Prasad Tripathi   +3 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source