Results 151 to 160 of about 740,350 (265)

Exploitation of combining ability and heterotic potential of okra under the sub-mountain region of Himalayan. [PDF]

Sci Rep
Pathania R, Singh A, Mehta DK, Bhardwaj RK, Tariq M, Garg S, Jain M, Mohammed A, Gangola S, Mittal A.   +9 more
europepmc   +1 more source

Evaluation of salinity resistance and combining ability analysis in the seedlings of mulberry hybrids (Morus alba L.). [PDF]

Physiol Mol Biol Plants, 2023
Chen X, Gao Y, Zhang D, Gao Y, Song Y, Wang H, Ma B, Li J.   +7 more
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Sparse testcrossing for early-stage genomic prediction of general combining ability to increase genetic gain in maize hybrid breeding programs. [PDF]

Theor Appl Genet
González-Diéguez DO, Atlin GN, Beyene Y, Wegary D, Gemenet DC, Werner CR.   +5 more
europepmc   +1 more source

Correction to: Evaluation of salinity resistance and combining ability analysis in the seedlings of mulberry hybrids (Morus alba L.). [PDF]

Physiol Mol Biol Plants, 2023
Chen X, Gao Y, Zhang D, Gao Y, Song Y, Wang H, Ma B, Li J.   +7 more
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Analysis of combining ability and stability of yield characteristics of upland cotton in two years. [PDF]

PeerJ
Ma X, Guo W, He L, Cao X.
europepmc   +1 more source

Combining Ability Analysis of Yield-Related Traits of Two Elite Rice Restorer Lines in Chinese Hybrid Rice. [PDF]

Int J Mol Sci, 2023
Wang S, Wu H, Lu Z, Liu W, Wang X, Fang Z, He X.   +6 more
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Estimation of heterosis and combining ability under low soil phosphorus condition in rice (Oryza sativa L.). [PDF]

Sci Rep
Madhusudan N, Senguttuvel P, Sundaram RM, Anantha MS, Gobinath R, Prasad ASH, Subrahmanyam D, RadhaKrishna KV.   +7 more
europepmc   +1 more source