A Seven-Parent Diallel Cross in Onions to Evaluate General and Specific Combining Ability and their Interaction with Years and Locations1 [PDF]
, 1977 George L. Hosfield +2 more
openalex +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Combining Ability Estimates in Arachis Hypogaea L. III. F2 Generation of Intra- and Intersubspecific Crosses1 [PDF]
, 1975 J. C. Wynne, J. O. Rawlings, D. A. Emery
openalex +1 more source
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
PlantsTo ensure food and feed security, modern maize hybrids must not only perform well under changing climate conditions but also consistently achieve higher and stable yields, exhibit maximum tolerance to stress factors, and produce high quality grains. In a
Călin Popa +10 more
doaj +1 more source
Understanding the combining ability of nutritional, agronomic and industrial traits in soybean F2 progenies. [PDF]
Sci Rep, 2023 das Chagas PHM +7 more
europepmc +1 more source
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
Molecular Oncology, EarlyView.The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche +8 more
wiley +1 more source
Combining ability of unselected inbred lines of corn from incomplete diallel and top-cross tests
, 1959 Stanley Dean Jensen
openalex +1 more source
Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
Hybrid breeding for fall armyworm resistance: Combining ability and hybrid prediction. [PDF]
Plant Breed, 2023 Kamweru I +5 more
europepmc +1 more source