Results 181 to 190 of about 10,435,327 (303)

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Combining ability of banana triploid hybrid progenitors and genomic prediction of cross performance for agro-morphological traits. [PDF]

Genetics
Toniutti L, Rio S, Madec C, Ricci S, Guiougou C, Marius F, Mina C, Delos JE, Lambert F, Efile JC, D'Hont A, Martin G, Hoarau JY, Salmon F.   +13 more
europepmc   +1 more source

Heterosis and combining ability of iron, zinc and their bioavailability in maize inbred lines under low nitrogen and optimal environments. [PDF]

Heliyon, 2023
Akhtar S, Mekonnen TW, Mashingaidze K, Osthoff G, Labuschagne M.   +4 more
europepmc   +1 more source

Combining ability for yield and fruit quality in the pepper Capsicum annuum.

Genetics and Molecular Research, 2014
N. F. F. do Nascimento, E. R. do Rêgo, M. F. Nascimento, C. Bruckner, F. Finger, M. M. do Rêgo   +5 more
semanticscholar   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Corrigendum: Testcross performance and combining ability of intermediate maturing drought tolerant maize inbred lines in Sub-Saharan Africa. [PDF]

Front Plant Sci
Manigben KA, Beyene Y, Chaikam V, Tongoona PB, Danquah EY, Ifie BE, Aleri I, Chavangi A, Prasanna BM, Gowda M.   +9 more
europepmc   +1 more source

Estimating the combining ability and genetic parameters for growth habit, yield, and fiber quality traits in some Egyptian cotton crosses. [PDF]

BMC Plant Biol, 2023
Abdel-Aty MS, Sorour FA, Yehia WMB, Kotb HMK, Abdelghany AM, Lamlom SF, Shah AN, Abdelsalam NR.   +7 more
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Combining ability and gene action for resistance to Fusarium ear rot in tropical maize hybrids. [PDF]

Front Plant Sci
Ayesiga SB, Rubaihayo P, Sempiira JB, Adjei EA, Dramadri IO, Oloka BM, Sserumaga JP.   +6 more
europepmc   +1 more source

Combining ability and heterosis for concentration of mineral elements and protein in common bean (Phaseolus vulgaris L.)

, 2014
E. Ceyhan, M. Harmankaya, A. Kahraman
semanticscholar   +1 more source