Results 91 to 100 of about 81,496 (301)

Long‐Term Safety and Efficacy of Mepolizumab in Eosinophilic Granulomatosis With Polyangiitis

Arthritis &Rheumatology, Accepted Article.
Objectives Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare, relapsing, inflammatory disease. Management of EGPA predominantly relies on oral corticosteroids (OCS), which are associated with many adverse effects. The Phase III MIRRA trial demonstrated efficacy and safety of mepolizumab, anti‐interleukin‐5 biologic, for EGPA.
Michael E Wechsler, Jared Silver, Gerhard Wolff, Robert G Price, Rejina Verghis, Peter F Weller, Peter A Merkel, Paneez Khoury, on behalf of the EGPA Mepolizumab Open‐Label Extension study group, Arnaud Bourdin, Pascal Chanez, Anoop Chauhan, Vincent Cottin, Gerald Gleich, Berhnard Hellmich, Tomonori Ishii, David Jayne, Jean‐Emmanuel Kahn, Peter Kern, Nader Khalidi, Ina Koetter, Carol Langford, Amy Markezich, Paul Monach, Shamsa Naveed, Peter Oelzner, Kenneth Pinna, Xavier Puechal, Emory H Robinette, Florence Roufosse, Reinhard Voll, Andrew Schafer, Kaharu Sumino, Masami Taniguchi, Phillip Lieberman   +34 more
wiley   +1 more source

German guideline diverticular disease/diverticulitis

United European Gastroenterology Journal, Volume 10, Issue 9, Page 923-939, November 2022., 2022
Abstract Diverticulosis and diverticular disease are ranked among the most common gastroenterological diseases and conditions. While for many years diverticulitis was found to be mainly an event occurring in the elder population, more recent work in epidemiology demonstrates increasing frequency in younger subjects.
Wolfgang Kruis, Christoph‐Thomas Germer, Stephan Böhm, Franz L. Dumoulin, Thomas Frieling, Jochen Hampe, Jutta Keller, Martin E. Kreis, Alexander Meining, Joachim Labenz, Johann F. Lock, Jörg P. Ritz, Andreas Schreyer, Ludger Leifeld, for the German Society of Gastroenterology, Digestive and Metabolic Diseases (DGVS) and the German Society of General and Visceral Surgery (DGAV) (AWMF‐Register 021‐20)   +15 more
wiley   +1 more source

Detectability of Sungrazing Comet Soft X-ray Irradiance [PDF]

Journal of Astronomy and Space Sciences, 2007
Originating from the Oort cloud, some comets disappear to impact against the Sun or to split up by strong gravitational force. Then they don't go back to the Oort cloud. They are called sungrazing comets.
Su Yeon Oh, Yu Yi, Jakyoung Nah, Yong Ha Kim   +3 more
doaj   +1 more source

The Slow‐Rotating Nucleus of Comet C/2013 R1 (Lovejoy)

Astronomische Nachrichten, EarlyView.
ABSTRACT The close approach of comet C/2013 R1 (Lovejoy) allowed us to conduct an in‐depth study of the morphology of the inner coma. From the measurement of the dust emission structures expanding near the cometary nucleus in November–December 2013, we derived a slow rotation period of 47.8±1.2$$ 47.8\pm 1.2 $$ h.
Federico Manzini, Virginio Oldani, Andrea Farina, Paolo Ochner, Andrea Reguitti, Luigi R. Bedin, Jean Gabriel Bosch, Erik Bryssinck, Roberto Crippa, Stéphan Gaumont‐Guay, Carl W. Hergenrother, Joel Nicolas, Ivo Scheggia   +12 more
wiley   +1 more source

Comets in Australian Aboriginal Astronomy [PDF]

arXiv, 2010
We present 25 accounts of comets from 40 Australian Aboriginal communities, citing both supernatural perceptions of comets and historical accounts of bright comets. Historical and ethnographic descriptions include the Great Comets of 1843, 1861, 1901, 1910, and 1927.
arxiv  

Unidentified Infrared Emission Features in Mid-infrared Spectrum of Comet 21P/Giacobini-Zinner [PDF]

, 2019
Comet 21P/Giacobini-Zinner (hereafter, comet 21P/G-Z) is a Jupiter-family comet and a parent comet of the October Draconids meteor shower. If meteoroids originating from a Jupiter-family comet contain complex organic molecules, such as amino acids, they are essential pieces of the puzzle regarding the origin of life on Earth.
arxiv   +1 more source

Special Collection: Women of Catalysis 2024   NADH Driven Enzymatic Carboxylic Acid Reduction

ChemCatChem, Accepted Article.
Carboxylic acid reductases (CARs) are versatile biocatalysts for aldehyde production from carboxylic acids. The redox co‐factor utilized by CARs is NADPH and no explicitly NADH dependent CARs have been described so far. Especially in view of cell free applications which necessitate cofactor recycling, NADH dependent enzymes are more appealing due to ...
Jonathan Guyang Ling, Hannah G. Breuer, Holly Stolterfoht-Stock, Farah Diba Abu Bakar, Margit Winkler   +4 more
wiley   +1 more source

Near-Earth Asteroids as Possible Parent Bodies of Meteor Streams [PDF]

Учёные записки Казанского университета: Серия Естественные науки, 2016
The genetic relationship of meteor streams with near-Earth asteroids (NEAs) is being actively studied. A genetic link with the asteroid is possible only for streams in which meteoroids have the geocentric speed smaller than 50 km/s, thereby meaning the ...
M.G. Sokolova, M.V. Sergienko
doaj  

In Vitro Psilocybin Synthesis by Co‐Immobilized Enzymes

Chemistry – A European Journal, Accepted Article.
Advanced clinical trials investigate the Psilocybe magic mushroom natural product psilocybin as a treatment against major depressive disorder. Currently, synthetic material is used to meet the demand for legitimate pharmaceutical purposes. Here, we report an in vitro approach to biocatalytically produce psilocybin on a solid‐phase matrix charged with ...
Tim Schäfer, Alexander Sherwood, Thomas Kirkland, Thomas Krüger, Jakob Worbs, Olaf Kniemeyer, Markus Gressler, Dirk Hoffmeister   +7 more
wiley   +1 more source

The problem of the abolition of slavery and maritime rights on U.S. vessels with regards to British American relations in the first half of the 19th century

Przegląd Nauk Historycznych, 2020
The article analyses the struggle of Anglo-American relations connected to slaves and maritime rights on the sea from 1831 to 1842. The study is based on monographs, reports, treaties and correspondences between the two countries from the explosion of ...
Nguyen Van Sang, Jolanta A. Daszyńska
doaj   +1 more source