Results 91 to 100 of about 225,144 (339)

Assessing the Nature of Human Brain‐Derived Extracellular Vesicles on Synaptic Activity Via the Development of an Air‐liquid Microfluidic Platform

open access: yesAdvanced Science, EarlyView.
This seminal study highlights the interwoven and tightly regulated functions of brain‐derived extracellular vesicles. Using microfluidics, proteomics, and AI‐based electric signal analyses of cortical brain explants, this work provides a useful resource dataset revealing the composition of human brain‐derived extracellular vesicles obtained from ...
Corentin Bernou   +14 more
wiley   +1 more source

Chemical abundance of comets [PDF]

open access: yes
Observations of NH2, (OI) and molecular ion spectra in comets represent virtually all of the volatile fraction of a comet nucleus. Their study leads to the N2, NH3, H2O, CO2, CO content of the nucleus, and thus to important constraints on models of comet
Wehinger, Peter, Wyckoff, Susan
core   +1 more source

Bimetallic Nanozyme Amplifier for Synergistic Ferroptosis‐Cuproptosis and Metabolic Reprogramming to Reshape Immunosuppressive Tumor Microenvironment

open access: yesAdvanced Science, EarlyView.
The Bimetallic Nanozyme Amplifier (PEG@AuCZ@CC) to maximize hydrogen peroxide production and reprogram tumor metabolism from glycolysis to oxidative phosphorylation. This shift enhances ferroptotic/cuproptotic signaling cascades and creates a glucose‐enriched but lactate‐depleted tumor microenvironment (TME), effectively overcoming immune tolerance in ...
Jianzhang Luo   +9 more
wiley   +1 more source

Near-Earth Asteroids as Possible Parent Bodies of Meteor Streams [PDF]

open access: yesУчёные записки Казанского университета: Серия Естественные науки, 2016
The genetic relationship of meteor streams with near-Earth asteroids (NEAs) is being actively studied. A genetic link with the asteroid is possible only for streams in which meteoroids have the geocentric speed smaller than 50 km/s, thereby meaning the ...
M.G. Sokolova, M.V. Sergienko
doaj  

Comprehensive Measurement of Inter‐Individual Variation in DNA Repair Capacity in Healthy Individuals

open access: yesAdvanced Science, EarlyView.
Susceptibility to the health effects of DNA damage depends on a person's ability to repair DNA damage, but DNA repair has been difficult to measure in populations. A functional assay called FM‐HCR is used to measure DNA repair in 6 major pathways across 56 individuals.
Ting Zhai   +7 more
wiley   +1 more source

Single‐Cell Nucleus Extraction with Cellular Indexing

open access: yesAdvanced Science, EarlyView.
VacTrap is a multilayer, high‐throughput microfluidic system that isolates and spatially indexes single nuclei from hundreds of cells within minutes. Using dissolvable hydrogel trapdoors triggered by chemical and vacuum actuation, VacTrap synchronously transfers nuclei while preserving spatial links to parent cells.
Trinh Lam   +7 more
wiley   +1 more source

Chemical Risks, Genotoxicity, and Oxidative Stress in Healthcare Workers

open access: yesToxics
Background/Objectives Using genotoxicity tests and oxidative stress indicators, the study evaluated the relationship between healthcare workers’ (HCWs) exposure to chemical risks. This study aimed to evaluate the oxidative damage and genotoxic effects of
Ayşe Coşkun Beyan   +3 more
doaj   +1 more source

GALEX FUV Observations of Comet C/2004 Q2 (Machholz): The Ionization Lifetime of Carbon

open access: yes, 2010
We present a measurement of the lifetime of ground state atomic carbon, C(^3P), against ionization processes in interplanetary space and compare it to the lifetime expected from the dominant physical processes likely to occur in this medium.
Axford   +29 more
core   +1 more source

The changing comet

open access: yesThe Journal of Headache and Pain, 2017
Editorial
openaire   +4 more sources

Crater Observing Bioinspired Rolling Articulator (COBRA)

open access: yesAdvanced Intelligent Systems, EarlyView.
Crater Observing Bio‐inspired Rolling Articulator (COBRA) is a modular, snake‐inspired robot that addresses the mobility challenges of extraterrestrial exploration sites such as Shackleton Crater. Incorporating snake‐like gaits and tumbling locomotion, COBRA navigates both uneven surfaces and steep crater walls.
Adarsh Salagame   +4 more
wiley   +1 more source

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