Results 161 to 170 of about 8,464 (293)

ID3 deficiency alters chromatin accessibility at DSB sites and enhances vulnerability to HDAC inhibition

open access: yesInternational Journal of Cancer, Volume 158, Issue 12, Page 3173-3186, 15 June 2026.
What's new? Errors in DNA double‐strand break (DSB) repair can lead to mutations, chromosomal instability, and ultimately cancer. Inhibitor of DNA‐binding 3 (ID3), a transcriptional repressor, is crucial to promoting DSB repair and helping maintain genome stability. Here, the authors investigated ID3 regulation of DNA repair via chromatin accessibility
Giuditta Della Corte   +10 more
wiley   +1 more source

Destruction of Sun-Grazing Comet C-2011 N3 (SOHO) Within the Low Solar Corona

open access: yes, 2012
Observations of comets in Sun-grazing orbits that survive solar insolation long enough to penetrate into the Suns inner corona provide information on the solar atmosphere and magnetic field as well as on the makeup of the comet. On 6 July 2011, the Solar
Schrijver, C. J.   +6 more
core  

Dynamical evolution of Halley-type comets [PDF]

open access: yesMonthly Notices of the Royal Astronomical Society, 1996
M. E. Bailey, V. V. Emel'yanenko
openaire   +1 more source

Dual‐Peptide Nanoplatform: Mesoporous Silica Nanoparticles Functionalized With a Cell‐Penetrating Peptide and Loaded With Rationally Designed Antimicrobial Peptides for Tuberculosis Therapy

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 21, 5 June 2026.
Machine learning–guided engineering of a plectasin‐derived peptide yields DC05, a potent antimycobacterial candidate. Encapsulation into tuftsin‐functionalized mesoporous silica nanoparticles enhances intracellular delivery, stability, and activity against Mycobacterium tuberculosis while maintaining low cytotoxicity and minimal hemolysis. The combined
Christian S. Carnero Canales   +12 more
wiley   +1 more source

Comet Hitchhiker: NIAC Phase 1 Final Report

open access: yes, 2018
Summary of Activities-Developed the Comet Hitchhiker concept, which is to hitch rides on small bodies (asteroids and comets) using a tethered spacecraft. (Section 2)-Identified five scientifically important missions that would be enabled or significantly
Grip, Havard F.   +7 more
core  

Microtubule dynamics in adult retinal ganglion cells and dorsal root ganglion neurons. [PDF]

open access: yesFront Mol Neurosci
Vecino E   +8 more
europepmc   +1 more source

DMAP1 Deficiency Suppresses Lung Cancer Progression by Destabilizing Replication Fork and Activating IFN Signaling‐Mediated Anti‐tumor Immunity

open access: yesAdvanced Science, Volume 13, Issue 33, 15 June 2026.
Lung cancer remains the leading cause of cancer‐related death. We investigated the role of the epigenetic regulator DMAP1 in NSCLC and found that its loss induces replication stress and DNA damage. This in turn activates type I IFN signaling via the cGAS–STING pathway and transcriptional ISG de‐repression, enhancing anti‐tumor immune responses ...
Kan Huang   +10 more
wiley   +1 more source

The EUV Emission in Comet-Solar Corona Interactions

open access: yes, 2011
The Atmospheric Imaging Assembly (AlA) on the Solar Dynamics Observatory (SDO) viewed a comet as it passed through the solar corona on 2011 July 5. This was the first sighting of a comet by a EUV telescope. For 20 minutes, enhanced emission in several of
Saint-Hilaire, Pasal   +7 more
core  

Emerging Trends in HIV-1 Sub-Subtype A6 in Belgium: Transmission Dynamics, Drug Resistance, and Subtyping Tool Evaluation. [PDF]

open access: yesViruses
Mortier V   +18 more
europepmc   +1 more source

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