Results 71 to 80 of about 7,430 (235)

Cellular Responses to Tartrazine and Sulfanilic Acid Exposure in BEAS‐2B Cells: Viability, Apoptosis, and DNA Damage

Journal of Applied Toxicology, EarlyView.
ABSTRACT Tartrazine is a synthetic azo dye widely used in food, pharmaceutical, and cosmetic products, resulting in extensive human exposure, while its toxicity and that of its primary metabolite, sulfanilic acid, remain controversial. Considering the reported association of tartrazine with hypersensitivity and allergic‐like reactions, human bronchial ...
Merve Baysal, Abdullah Burak Karaduman, Büşra Korkut Çelikateş, Merve Güven, Özlem Atlı‐Eklioğlu, Sinem Ilgın   +5 more
wiley   +1 more source

Analyzing the Onset of Cometary Activity by the Jupiter-family Comet 2023 RN3

The Astronomical Journal
We utilize serendipitous observations from the Asteroid Terrestrial-impact Last Alert System (ATLAS) and the Zwicky Transient Facility in addition to targeted follow-up observations from the Las Cumbres Observatory (LCO) and Liverpool Telescope to ...
Matthew M. Dobson, Megan E. Schwamb, Alan Fitzsimmons, Michael S. P. Kelley, Carrie E. Holt, Joseph Murtagh, Henry H. Hsieh, Larry Denneau, Nicolas Erasmus, A. N. Heinze, Luke J. Shingles, Robert J. Siverd, Ken W. Smith, John L. Tonry, Henry Weiland, David. R. Young, Tim Lister, Edward Gomez, Joey Chatelain, Sarah Greenstreet   +19 more
doaj   +1 more source

From patient notes to prognostication: The revolutionary potential of event‐based foundation models in orthopaedics

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract The integration of artificial intelligence (AI)‐equipped tools into electronic health record (EHR) platforms may drive the evolution of orthopaedic diagnosis and decision‐making, leveraging big data to generate precise and context‐aware insights.
Alexander M. Bouterse, James A. Pruneski, Felix C. Oettl, Bálint Zsidai, Umile Giuseppe Longo, Thomas Tischer, Michael T. Hirschmann, Kristian Samuelsson   +7 more
wiley   +1 more source

DNA Damaging Effects, Oxidative Stress Responses and Cholinesterase Activity in Blood and Brain of Wistar Rats Exposed to Δ⁹-Tetrahydrocannabinol

Molecules, 2019
Currently we are faced with an ever-growing use of Δ9-tetrahydrocannabinol (THC) preparations, often used as supportive therapies for various malignancies and neurological disorders.
Nevenka Kopjar, Nino Fuchs, Suzana Žunec, Anja Mikolić, Vedran Micek, Goran Kozina, Ana Lucić Vrdoljak, Irena Brčić Karačonji   +7 more
doaj   +1 more source

Identification of Novel Interacting Proteins of FUZ and GPR161

PROTEOMICS, EarlyView.
ABSTRACT Protein–protein interactions are central to the dynamic regulation of signaling pathways and provide critical insight into the cellular mechanisms underlying human disease. Our previous study demonstrated biochemical and genetic interactions between FUZ and GPR161 in sonic hedgehog signaling during spinal neural tube development. In this study,
Gabriella Salazar, Anna Battenhouse, Andrew J. Kim, Sung‐Eun Kim   +3 more
wiley   +1 more source

Application of Non‐Isothermal Network Theory With Curved‐Channel Element Characteristics to Predict Melt Conveying in High‐Performance Single‐Screw Extruders

Journal of Polymer Science, EarlyView.
This study presents a fast and accurate calculation tool to predict conveying of polymer melts in single‐screw extruders. Integrating generalized sub‐models into network theory allows to represent the complex screw shapes and material behavior more realistically. Tests on an industrial extruder show close agreement with experiments, outperforming older
Daniel Herzog, Wolfgang Roland, Christian Marschik, Gerald Berger‐Weber   +3 more
wiley   +1 more source

Baicalein Sensitizes Radioresistant BT549 and MCF7‐R Breast Cancer Cells by Modulating Rac1 Signaling

Phytotherapy Research, EarlyView.
ABSTRACT Radioresistance remains a key barrier in breast cancer (BC) treatment. Baicalein, a flavonoid from Scutellaria baicalensis, has shown potential to enhance radiosensitivity. This study investigates its efficacy and mechanism in radioresistant BC models. Radioresistant BC cell models were established via fractionated irradiation and validated by
Zitong Zhao, Zhangyun Li, Quanzhou Peng, Shuqun Zhang   +3 more
wiley   +1 more source

The thrombin receptor (PAR1) is associated with microtubules, mitosis and process formation in glioma cells

Heliyon
The cell surface protease-activated receptor 1 (PAR1) is overexpressed in glioblastoma multiforme (GBM). We studied the function and structure of intracellular microtubule (MT) and PAR1 in a tubulin-mediated process.
Valery Golderman, Shany Guly Gofrit, Yanina Ivashko-Pachima, Illana Gozes, Joab Chapman, Efrat Shavit-Stein   +5 more
doaj   +1 more source

The Comet Assay for the Evaluation of Genotoxic Potential of Landfill Leachate

The Scientific World Journal, 2012
Genotoxic assessment of landfill leachate before and after biological treatment was conducted with two human cell lines (Me45 and NHDF) and Daphnia magna somatic cells. The alkali version of comet assay was used to examine genotoxicity of leachate by DNA
Kamila Widziewicz, Joanna Kalka, Magdalena Skonieczna, Paweł Madej   +3 more
doaj   +1 more source

From Flybys to Sample Return: A Review of Space Probes and Robotic Sampling Technologies for Small Bodies

Journal of Field Robotics, EarlyView.
ABSTRACT As a crucial puzzle piece of deep space exploration, exploring small bodies can provide significant scientific insights and valuable mineral resources. Unlike missions to the Moon and Mars, small‐body missions pose distinct technical challenges, including communication delays, weak gravity, and uncertain environments. This paper reviews a full
Xin Zhang, Hao Zhou, Dalin Zhou, Zhaojie Ju   +3 more
wiley   +1 more source