Results 51 to 60 of about 39,671 (263)

Detailed plan for the COMET WP3 initial research activity - list of research projects and goals, participants and timing [PDF]

open access: yes, 2013
Detailed plan for the COMET Work Package (WP ...
Barnett, Catherine L.   +27 more
core  

Exploring the volatile composition of comets C/2012 F6 (Lemmon) and C/2012 S1 (ISON) with ALMA [PDF]

open access: yes, 2017
Comets formed in the outer and cold parts of the disk which eventually evolved into our Solar System. Assuming that the comets have undergone no major processing, studying their composition provides insight in the pristine composition of the Solar Nebula.
Agúndez   +35 more
core   +3 more sources

Inhibition of SIRT7 Overcomes Radioresistance in Pancreatic Neuroendocrine Tumors by Reactivating MEN1 Expression

open access: yesAdvanced Science, EarlyView.
Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang   +11 more
wiley   +1 more source

The First Quantitative Study of Cometary Tail Regrowth following a Coronal Mass Ejection-driven Disconnection Event

open access: yesThe Astrophysical Journal
Comet C/2023 P1 (Nishimura) was observed by the Solar Orbiter Heliospheric Imager (SoloHI), on board the Solar Orbiter spacecraft, from 2023 September 1 to 14.
Shaheda Begum Shaik   +5 more
doaj   +1 more source

MIR Spectra and Analysis of Jovian Trojan Asteroids

open access: yesThe Planetary Science Journal, 2023
Jovian Trojan asteroids make up a large group of primitive bodies that populate Jupiter's L4 and L5 Lagrange points. The Trojans’ dynamics and composition carry insight into the formation mechanisms that shaped our solar system. Mid-infrared (MIR; 5–35 μ
Audrey C. Martin, Joshua P. Emery
doaj   +1 more source

Time-frequency analysis of the restricted three-body problem: transport and resonance transitions [PDF]

open access: yes, 2004
A method of time-frequency analysis based on wavelets is applied to the problem of transport between different regions of the solar system, using the model of the circular restricted three-body problem in both the planar and the spatial versions of the ...
Marsden, Jerrold E.   +1 more
core   +2 more sources

Macrophage Extracellular Traps in Immunity and Cancer

open access: yesAdvanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li   +5 more
wiley   +1 more source

On the Early Thermal Processing of Planetesimals during and after the Giant Planet Instability

open access: yesThe Planetary Science Journal
Born as ice-rich planetesimals, cometary nuclei were gravitationally scattered onto their current orbits in the Kuiper Belt and the Oort Cloud during the giant planets’ dynamical instability in the early stages of our solar system’s history.
Anastasios Gkotsinas   +4 more
doaj   +1 more source

Where do long-period comets come from? 26 comets from the non-gravitational Oort spike [PDF]

open access: yes, 2010
The apparent source region (or regions) of long-period comets as well as the definition of the dynamically new comet are still open questions.The aim of this investigation is to look for the apparent source of selected long period comets and to refine ...
Biver   +32 more
core   +1 more source

Glutamine Deprivation Triggers Tribbles Homolog 3 Dependent G‐Quadruplex Resolution to Maintain DNA Repair and Tumor Survival

open access: yesAdvanced Science, EarlyView.
Glutamine deprivation triggers transient DNA damage yet activates adaptive repair in hepatocellular carcinoma cells. We identify TRIB3 as a stress‐induced nuclear scaffold that associates with DDX5 and G‐quadruplex DNA atBRCA1 andRAD51AP1 promoters. TRIB3 loss increases G4 accumulation, suppresses HR gene transcription, elevates γ‐H2A.X, and sensitizes
Qiang Ji   +10 more
wiley   +1 more source

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