Results 141 to 150 of about 2,128 (236)

Direct evidence of singlet molecular oxygen [O2 (1Δg)] production from UVA excited 6‐thioguanine

Photochemistry and Photobiology, EarlyView.
6‐Thioguanine (6‐TGua) is incorporated into DNA as a purine analogue, inhibiting cell replication. Patients treated with 6‐TGua are more prone to developing skin cancer due to the photoexcitation of 6‐TGua by UVA radiation (as illustrated in the Jablonski diagram). Upon exposure to UVA, the excited 6‐TGua generates 1O2.
André L. Lopes, Fernanda M. Prado, Helena C. Junqueira, Marisa H. G. Medeiros, Graziella E Ronsein, Jean Cadet, Paolo Di Mascio   +6 more
wiley   +1 more source

Targeting MCM6 Enhances Melphalan Chemosensitivity in Retinoblastoma by Modulating DNA Damage Response. [PDF]

Invest Ophthalmol Vis Sci
Wang M, Tang J, Li J, Lv J, Zhang Z, Liu Y, Sun H, Gao Y, Chen S, Tang L, Zhang P, Su S, Lu R.   +12 more
europepmc   +1 more source

RAD51 and RAD51 paralog inhibition sensitizes nonreplicating quiescent keratinocytes to UV radiation

Photochemistry and Photobiology, EarlyView.
UV radiation and other compounds generate DNA adducts that block transcription and induce cell death if not removed by the nucleotide excision repair system. In this work, we used a small‐scale pharmacological screen to discover that inhibition of the recombinase RAD51 sensitized nonreplicating quiescent keratinocytes to both UVR and other agents that ...
Saman Khan, Angitha Nair, M. Alexandra Carpenter, Michael G. Kemp   +3 more
wiley   +1 more source

Neutral lipids restrict the mobility of broken DNA molecules during comet assays. [PDF]

Biol Cell
Soulet C, Josa-Castro J, Moriel-Carretero M.   +2 more
europepmc   +1 more source

UniScore, a Unified and Universal Measure for Peptide Identification by Multiple Search Engines. [PDF]

Mol Cell Proteomics
Tabata T, Yoshizawa AC, Ogata K, Chang CH, Araki N, Sugiyama N, Ishihama Y.   +6 more
europepmc   +1 more source

Origin and Formation of Comets [PDF]

Nature, 1949
openaire   +1 more source

Alternation of must, have to, and need to in English as a lingua franca

World Englishes, EarlyView.
Abstract This study explores the grammatical variability of modal auxiliary verbs in English as a lingua franca. Focusing on the ongoing change must, have to, and need to, this research utilizes two spoken corpora: the Vienna–Oxford International Corpus of English (VOICE) and the Asian Corpus of English (ACE).
Chunyuan Nie, Lea Meriläinen, Mikko Laitinen   +2 more
wiley   +1 more source

A multidimensional study on the effects of Abelmoschus esculentus (L.) Moench extract in uranyl acetate-exposed Allium cepa L. [PDF]

Sci Rep
Üst Ö, Kalefetoğlu Macar T, Macar O, Yalçın E, Çavuşoğlu K, Kutluer F.   +5 more
europepmc   +1 more source

Protective effects of Paeonia suffruticosa callus extract in skin through anti-inflammation and repair UVB-induced damage. [PDF]

Int J Cosmet Sci
Li Y, Han J, Gong R, Liu Y, Zhou Y, Gong T, Wang B, Zhang L, Li S, Chen J.   +9 more
europepmc   +1 more source

P-selectin overexpression impairs hematopoietic stem cell homeostasis via inflammatory receptor-mediated proliferation and differentiation. [PDF]

Cell Death Dis
He W, Qiu H, Feng Y, Qiu Q, Zheng L, Pan C, Cui X, Sun Y, Wang B, Hu Y.   +9 more
europepmc   +1 more source