Results 161 to 170 of about 2,103,717 (319)

Advancing inducible gene-inactivation systems to explore synthetic lethality. [PDF]

NAR Cancer
Sánta ÁT, Gráf A, Vincze-Kontár K, Kovács K, Bóna B, Mórocz M, Kiss E, Haracska L.   +7 more
europepmc   +1 more source

Evaluating School‐Based Obesity Prevention Interventions in 6‐ to 12‐Year‐Old Children: A Scoping Review of All Reported Outcomes and Expert Consultation

Obesity Reviews, EarlyView.
ABSTRACT Introduction This scoping review aims to identify all outcomes reported in school‐based obesity prevention interventions in childhood. It serves as an essential first step towards developing an internationally agreed‐upon Core Outcome Set (COS), which defines what should be measured in all school‐based childhood obesity prevention studies ...
Teatske M. Altenburg, Lotte W. de Vries, Iris J. Grooten, Janneke van 't Hooft, Arend W. van Deutekom, Tessa Roseboom, Erica van den Akker, Michael Duncan, Ulf Ekelund, John J. Reilly, Lisa Reilly, Annette Stafleu, Martyn Standage, Mai J. M. Chinapaw, Deirdre M. Harrington   +14 more
wiley   +1 more source

DNA polymerase α/primase extraction from chromatin by VCP/p97 restricts ATR activation during unperturbed DNA replication. [PDF]

Nat Commun
Rodríguez-Acebes S, Martín-Rufo R, Gómez-Moya A, Churcher SB, Fernández-Llorente A, de la Vega-Barranco G, Perona A, Oroz P, Martín-Doncel E, Toledo LI, Méndez J, Lecona E.   +11 more
europepmc   +1 more source

Prolonged exposure to artificial light and carcinogenesis: A systematic review of oncostatic mechanisms associated with melatonin pathways

Photochemistry and Photobiology, EarlyView.
Exposure to artificial light at night (ALAN), particularly at blue wavelengths, disrupts circadian rhythms by suppressing melatonin, thereby increasing cancer susceptibility. This systematic review consolidates evidence linking prolonged ALAN exposure to an elevated risk of breast and prostate tumors.
Gabriel Barboza, Jêmina Oliveira, Antônio Ferreira, Renan Lopes, Marli Cupertino   +4 more
wiley   +1 more source

In vitro comparison of the imaging properties of dental materials in soft tissue using ultrasonography and cone beam computed tomography. [PDF]

Sci Rep
Şeker Ç, Kaya EY, Geduk G, Cicek O, İçen M.   +4 more
europepmc   +1 more source

Planetary perturbations and the origins of short-period comets

, 1990
T. Quinn, S. Tremaine, M. Duncan
semanticscholar   +1 more source

Direct evidence of singlet molecular oxygen [O2 (1Δg)] production from UVA excited 6‐thioguanine

Photochemistry and Photobiology, EarlyView.
6‐Thioguanine (6‐TGua) is incorporated into DNA as a purine analogue, inhibiting cell replication. Patients treated with 6‐TGua are more prone to developing skin cancer due to the photoexcitation of 6‐TGua by UVA radiation (as illustrated in the Jablonski diagram). Upon exposure to UVA, the excited 6‐TGua generates 1O2.
André L. Lopes, Fernanda M. Prado, Helena C. Junqueira, Marisa H. G. Medeiros, Graziella E Ronsein, Jean Cadet, Paolo Di Mascio   +6 more
wiley   +1 more source

CHK1 is an integral regulator of DNA replication in human cells. [PDF]

Cell Death Dis
Li S, Zhu D, Tang M, Huang M, Feng X, Nie L, Zhang H, Yin L, Keast S, Yang C, Ma T, Chen J.   +11 more
europepmc   +1 more source

RAD51 and RAD51 paralog inhibition sensitizes nonreplicating quiescent keratinocytes to UV radiation

Photochemistry and Photobiology, EarlyView.
UV radiation and other compounds generate DNA adducts that block transcription and induce cell death if not removed by the nucleotide excision repair system. In this work, we used a small‐scale pharmacological screen to discover that inhibition of the recombinase RAD51 sensitized nonreplicating quiescent keratinocytes to both UVR and other agents that ...
Saman Khan, Angitha Nair, M. Alexandra Carpenter, Michael G. Kemp   +3 more
wiley   +1 more source

The many origins of extremophile fishes. [PDF]

Proc Biol Sci
Brownstein CD, Harrington RC, Radchenko O, Near TJ.   +3 more
europepmc   +1 more source