PRDM1 restricts bladder cancer progression and enhances chemosensitivity by suppressing OTUD6A-mediated deubiquitination of CDC6. [PDF]
Cui J +9 more
europepmc +1 more source
Fish Sperm Subpopulations Detection, Separation, and Application: Current State and Trends
Modern advances in sperm biology highlight the necessity of recognising intra‐ejaculate heterogeneity as a central concept for advancing both the fundamental understanding of fertilisation processes and the development of artificial reproduction techniques in fishes. ABSTRACT Sperm subpopulations represent a fundamental manifestation of intra‐ejaculate
Viktoriya Dzyuba +2 more
wiley +1 more source
EP300 deficiency leads to chronic replication stress mediated by defective replication fork protection. [PDF]
Barreto-Galvez A +18 more
europepmc +1 more source
Alternation of must, have to, and need to in English as a lingua franca
Abstract This study explores the grammatical variability of modal auxiliary verbs in English as a lingua franca. Focusing on the ongoing change must, have to, and need to, this research utilizes two spoken corpora: the Vienna–Oxford International Corpus of English (VOICE) and the Asian Corpus of English (ACE).
Chunyuan Nie +2 more
wiley +1 more source
Multiple formation pathways for amino acids in the early Solar System based on carbon and nitrogen isotopes in asteroid Bennu samples. [PDF]
Baczynski AA +11 more
europepmc +1 more source
Updated Interior Structure of Callisto From a Reanalysis of Galileo Data
Abstract The internal structure of Callisto has been a long‐standing question since the Galileo mission. Previous analyses suggested a largely undifferentiated interior. We present an updated interior structure for Callisto derived from a reanalysis of Galileo's Doppler tracking data using new signal processing techniques.
G. Cascioli +5 more
wiley +1 more source
One‐electron oxidation of purine and pyrimidine bases of isolated and cellular DNA generates related reactive base radical cations that are converted into final decomposition products through deprotonation and hydration. In the case of guanine, the most susceptible nucleobase to one‐electron oxidants, 8‐hydroxy‐7,8‐dihydroguanyl radical, thus formed by
Jean Cadet +3 more
wiley +1 more source
The formation and function of intercellular bridges in male germlines. [PDF]
Cui J, Cheng J, Wu B, He A.
europepmc +1 more source
Data Analysis Planning and Reporting for Confirmatory Multi‐Lab Preclinical Trials: A Tutorial
ABSTRACT Confirmatory multi‐lab preclinical trials are a powerful experimental strategy to enable decisions to transition from preclinical to clinical settings. With their complexity, such study designs pose several challenges in statistical planning, analysis, and reporting of experiments.
María Arroyo‐Araujo +13 more
wiley +1 more source
Neutral lipids restrict the mobility of broken DNA molecules during comet assays. [PDF]
Soulet C +2 more
europepmc +1 more source

