Results 41 to 50 of about 8,090 (243)

The Dust-to-Gas Ratio, Size Distribution, and Dust Fall-Back Fraction of Comet 67P/Churyumov-Gerasimenko: Inferences From Linking the Optical and Dynamical Properties of the Inner Comae

Frontiers in Physics, 2020
In this work, we present results that simultaneously constrain the dust size distribution, dust-to-gas ratio, fraction of dust re-deposition, and total mass production rates for comet 67P/Churyumov-Gerasimenko.
Raphael Marschall, Johannes Markkanen, Selina-Barbara Gerig, Selina-Barbara Gerig, Olga Pinzón-Rodríguez, Nicolas Thomas, Nicolas Thomas, Jong-Shinn Wu   +7 more
doaj   +1 more source

Pro‐ATO/Allicin Liposomes for Dual‐Pathway Targeting of p53‐Mutant Tumors

Advanced Science, EarlyView.
Schematic illustration of the “pro‐ATO”/allicin liposomal strategy. Liposomal encapsulation improves the stability and bioavailability of both agents while masking allicin's odor. Upon release in the tumor microenvironment, ATO reactivates structural p53 mutants, and allicin inhibits ATR signaling while releasing H2S, collectively inducing synthetic ...
Xiaoling Xu, WeiYi Cheng, Menghang Yang, Li He, WeiYe Ren, JingQuan Chen, LiTing He, Dandan Bao, Zhihong Zhu, Lixin Wang, Qinghua Yao, Ji‐Gang Piao   +11 more
wiley   +1 more source

Using the database of coordinates of the major planets for the numerical integration of the equations of celestial bodies motion

Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2011
Databases of major planets coordinates are created on the basis of the numerical theory of movement of planets DE405. Numerical integration of the motion equations of small bodies of Solar system is realized using the received databanks. Extra efficiency
Vladimir P Radchenko, Dmitriy A Zausaev
doaj  

Clumpy Novel Mitochondrial Signatures in Irradiated Human Diabetic Buccal Cells: A Case Control Study

Medeniyet Medical Journal
Objective: This study aimed to determine the whole free mitochondria in type-2 diabetic buccal epithelial cells using a supravital stain called 'Janus Green B' and assess their behavior after exposure to near infrared light.
Surraj SUSAI, Mrudula CHANDRUPATLA, Sumitra SIVAKOTI, Govindrao N. KUSNENIWAR, Anand K. PYATI   +4 more
doaj   +1 more source

Elevated TRIM25 Impairs Poly (ADP‐ribose) Metabolism via PARG Degradation and Mediates Compression‐Induced Intervertebral Disc Degeneration

Advanced Science, EarlyView.
TRIM25 acts as a multifunctional hub driving intervertebral disc degeneration under mechanical stress. Mechanical compression significantly upregulates TRIM25 expression, establishing it as a key E3 ubiquitin ligase platform. TRIM25 targets PARG and Ku80 via distinct molecular interfaces, triggering their ubiquitination and degradation.
Zhangrong Cheng, Haiyang Gao, Wenbo Wu, Pengzhi Shi, Xianglong Chen, Zimu Yu, Wang Wu, Kangcheng Zhao, Cao Yang, Yukun Zhang   +9 more
wiley   +1 more source

Some Studies of Terrestrial Impact Cratering Rate

Open Astronomy, 2011
In 1984, a 28.4 Myr periodicity was detected in the ages of terrestrial impact craters and a 26 Myr periodicity in the epochs of mass extinctions of species.
Jetsu L.
doaj   +1 more source

Endogenous Amplification of Apoptosis via p53 Regulation using a Cascade Nanocatalytic Medicine

Advanced Science, EarlyView.
An engineered MOF nanomedicine (MAL) triggers cascade nanocatalysis in tumors, converting H2O2 and L‐Arg into cytotoxic peroxynitrite. This induces DNA damage, activates the p53 pathway, and amplifies mitochondrial apoptosis via the BAX/Bcl‐2/Caspase‐3 axis, effectively inhibiting colorectal cancer growth with high biocompatibility.
Tan Wu, Xiaoyue Xu, Dan Xu, Hui Zhang, Nan Wang, Yang Yang, Qian Chen, Shunjie Chen, Cheng Li   +8 more
wiley   +1 more source

The Interstellar Heritage of Comets

The Astronomical Journal
Comets have similar compositions to interstellar medium ices, suggesting at least some of their molecules may be inherited from an earlier stage of evolution.
Karen Willacy, Liton Majumdar, Boncho Bonev, Erika Gibb, Neil Dello Russo, Michael DiSanti, Ronald J. Vervack Jr., Nathan X. Roth   +7 more
doaj   +1 more source

Cepstrum Analysis of Terrestrial Impact Crater Records [PDF]

Journal of Astronomy and Space Sciences, 2008
Study of terrestrial impact craters is important not only in the field of the solar system formation and evolution but also of the Galactic astronomy. The terrestrial impact cratering record recently has been examined, providing short- and intermediate ...
Heon-Young Chang, Cheongho Han
doaj   +1 more source

Macrophage Extracellular Traps in Immunity and Cancer

Advanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li, Eugenie Nepovimova, Adam Grundel, Lukas Peter, Qinghua Wu, Kamil Kuca   +5 more
wiley   +1 more source