Results 31 to 40 of about 5,092 (261)
Jurnal Review PolitikThe designation of Hari Santri as a national commemoration has triggered pros and cons since the beginning. Traditional Islamic groups represented by Nahdlatul Ulama were the initiators of this official commemoration, and Muhammadiyah as the ...
Wildan Ulumul Fahmi
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Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Circuits of Memory: The War Memory Boom in Western Australia
Societies, 2012 In some Australian academic circles in the 1980s it was believed that, as the numbers of soldiers of the world wars declined over time, so would attendances at war remembrance ceremonies on Anzac Day and interest in war commemoration in general. Contrary
John R. Stephens
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Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
La fotografía y la Revolución mexicana. Nuevas perspectivas y enfoques
Caravelle, 2011 This article proposes an interpretation of Isidro Fabela’s personal vision, since he’s one of the main intellectuals of the Revolution, since he is a collector and also responsible for the classification prevailing in his photographic archives.
Alberto Del Castillo Troncoso
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Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
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Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
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Events as Milestones in the Urban History and Their Commemoration: The Spatial Aspect
Historia provinciae: журнал региональной истории, 2019 The article deals with different types of historical events that have become landmarks in urban history. Analysing the historical plans and maps of Cherepovets, the author shows how the events of urban history were reflected in various forms of ...
Solodyankina Olga
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