Results 41 to 50 of about 5,092 (261)
From Center to periphery and vice versa: The politics of toponyms in the transitional capital [PDF]
Glasnik Etnografskog Instituta SANU, 2008 This paper discusses the politics of street names in Belgrade since the beginning of 1990s until today. Given the central place of the capital city in the symbolic geography of the nation, subsequent cultural influences of the capitals' 'city text ...
Radović Srđan
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Kronos, 2010 This article examines recent contestations over the commemoration of King Makhado of the Venda at the town of Louis Trichardt in Limpopo Province, South Africa.
Mahunele Thotse
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Digithum, 2017 Amb motiu de la commemoració del centenari del naixement d’Adolfo Sánchez Vázquez el 2015, es van celebrar a Mèxic una sèrie d’homenatges entorn de la seva figura i del seu llegat.
Laura Angélica Moya López
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PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
Go East, Old Man: The Ritual Spaces of SS Veterans' Memory Work
Culture Unbound: Journal of Current Cultural Research, 2014 This article uses social-movement analysis to understand the rituals, memory-work and spatialties of Waffen-SS veterans and their sympathizers. Most social-movement analysis focuses on left-wing protesters; our concern is with the marginalized counter ...
Steffen Werther, Madeleine Hurd
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