Results 61 to 70 of about 29,910 (306)
Celebrating school remembrance days “rebooted”
Acta Politica Polonica, 2020 Historical remembrance days and related celebrations are part of a culture of remembrance and are characterized by processes such as the typical use of language in speeches or songs (Huszár, Prikler, forthcoming), and possibly the inclusion of tools ...
Ágnes Klein, Éva Szederkényi
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Landscape biographies of commemoration
Archaeological Approaches to and Heritage Perspectives on Modern Conflict, 2019 All social structures, ranging from world-wide cultural communities to local networks of individuals, develop more or less specific memory cultures to connect places, buildings and land to memories and notions of ancestry and origin.
M. V. D. Schriek
semanticscholar +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
DIMITRIE GUSTI ȘI BREXIT-UL. DE UNDE TREBUIE SĂ ÎNCEAPĂ O DISCUȚIE DESPRE EUROPA FEDERALĂ [PDF]
Revista de Știinţe Politice şi Relaţii Internaţionale, 2020 This year we celebrate the 140th anniversary of the birth of the sociologist Dimitrie Gusti. The best way to pay homage to him is to prove his overwhelming vitality of his interrogations and diagnoses.
DAN DUNGACIU
doaj
Roman Tombs and the Art of Commemoration
, 2019 The history of funerary customs in Rome contains many unanswered questions and controversial debates, especially concerning the significant developments of the second century CE. In this book, distinguished historian Barbara E.
B. Borg
semanticscholar +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
The politics of memory and commemoration: Armenian diasporic reflections on 2015
Nationalities Papers, 2018 The centenary year of the Armenian genocide witnessed an escalation in cultural production and both political and academic focus. This paper looks at some of the sites and spaces, physical and discursive, in which the centenary was marked. In particular,
Sossie Kasbarian
semanticscholar +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source