Results 31 to 40 of about 4,451 (299)
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Le Centenaire de la Grande Guerre fait l’objet de nombreuses commémorations. Sur le réseau social numérique Twitter, des millions de tweets l’évoquent.
Clavert Frédéric
doaj
In this paper, we propose to review some of the national commemorations thatbelong to the nineteenth century. Based on the experience of teaching a degree subject in the History Professorate of the Universidad Nacional de Mar del Plata, we intend to ...
María Laura Mazzoni +1 more
doaj +1 more source
Quand débute la Réforme en France ?
31 October 1517 is traditionally taken as the starting point for the Reformation, even if the date is controversial. But the French Reformation has no easily identifiable starting date.
Yves Krumenacker
doaj +1 more source
TRANSFORMATIVE HISTORY: AMERICAN MONUMENT-MAKING AND THE ROAD TO INCLUSIVE PUBLIC COMMEMORATIONS FOR BLACK AMERICAN VETERANS [PDF]
In this thesis, I survey American public commemorations about war, the military, and Black American veterans from the nineteenth century to the present.
Bendolph, Jeanette Dianne
core +1 more source
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
This article by a young researcher aims to analyse different phenomena of commemoration in Cyprus. Taking this divided country and society, we wish to highlight the specificity of commemorative territories and artefacts, such as memorials and museums in ...
Marie Pouillès Garonzi
doaj +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
The red or ‘Flanders’ poppy has become the ubiquitous emblem of British war commemorations, yet it is also becoming more hegemonic and militaristic: the poppy’s meaning has always been contested, but its dominant interpretation has become increasingly ...
Alexandre Christoyannopoulos (1252407)
core +1 more source

