Results 41 to 50 of about 4,451 (299)
Many Seasons Gone: Memory, History, and the Atlantic Slave Trade
NWIG, 2009 [First paragraph] African Voices of the Atlantic Slave Trade: Beyond the Silence and the Shame. Anne C. Bailey. Boston: Beacon Press, 2005. 289 pp. (Cloth US $ 26.00) Lose Your Mother: A Journey along the Atlantic Slave Route.
Ted Maris-Wolf
doaj
ReligionsSome of Spain’s greatest humanists—Juan Luis Vives, Antonio de Nebrija, Juan de Ávila, Luis de León, and Benito Arias Montano—were from a converso background.
Silvina Schammah Gesser
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
A Threatened British Identity? Rethinking the roles of commemorations in 21st century Britain [PDF]
, 2022 I løpet av det siste tiåret har minnesmarkeringer i Storbritannias offentlige rom fått mye oppmerksomhet som et resultat av et økt fokus på inkludering av forskjellige grupper i samfunnet.
Hatlegjerde, Eline Vada
core
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Public commemorations of the Scottish Wars of Independence, 1800-1939 [PDF]
, 2019 Marinell Ash famously referred to the latter half of the nineteenth century as experiencing a ‘strange death’ in interest in the Scottish historical past, but increasing evidence suggests this was not an entirely fair assessment.
Harrison, Laura Signe Hushagen
core
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Recherches & Travaux, 2020 Flaubert can be considered as a spokesperson for the opponents to commemorations. The writer not only stood up against these collective high-masses; after his death, he was also seen as a writer who was not eligible for such honors according to the point
Marie-Clémence Régnier
doaj +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source