Results 51 to 60 of about 58,057 (392)
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
This article by a young researcher aims to analyse different phenomena of commemoration in Cyprus. Taking this divided country and society, we wish to highlight the specificity of commemorative territories and artefacts, such as memorials and museums in ...
Marie Pouillès Garonzi
doaj +1 more source
The Yugoslav State Security Service and the Bleiburg Commemorations
This article, based overwhelmingly on primary sources produced by the Yugoslav State Security Service, provides a historical overview of their work with respect to the commemorations at Bleiburg.
C. Nielsen
semanticscholar +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
A review of Smith, Mark S. Poetic Heroes: Literary Commemorations of Warriors and Warrior Culture in the Early Biblical World. Grand Rapids, MI: Eerdmans, 2014. xxiv1636 pp. $55.00 (paper)
Doak, Brian R.
core +2 more sources
The article compares dominant attitudes regarding November 11 in Poland and France. In both states, this date, which is related to the end of World War I and the restoration of the independence of Poland in 1918, constitutes a public holiday.
Bartłomiej Różycki, Geoffrey Lefebvre
doaj +1 more source
Sanctifying Minority Status in the Himalayan \u3ci\u3eUmmah\u3c/i\u3e: Eid al-Ghadeer Commemorations among the Shia in Leh, Ladakh [PDF]
Drawing on ethnographic data, this article argues that the Shia in Leh, Ladakh employ religious ceremonies such as Eid al-Ghadeer to construct a sense of sacred community and a sanctified minority status within the Himalayan ummah.
Singh, Rohit
core +1 more source
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source

