Results 51 to 60 of about 32,214 (336)

Symbolic legacies of slavery in Guyana

open access: yesNWIG, 2008
Focusses on the commemoration and symbolic functions of the slavery past in the Americas, with a particular focus on Guyana. Author explains that while symbolic representations of the legacies of slavery increased in the Americas since the 1960s, the ...
Alvin O. Thompson
doaj  

The First World War Centenary in the UK: ‘A Truly National Commemoration’? [PDF]

open access: yes, 2014
Prime Minister David Cameron has called for ‘a truly national commemoration of the First World War’. This article shows this to be problematic, politicised and contested. This is in part due to the elision of English and British histories.
Andrew Mycock   +6 more
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Book review: history, heritage and tradition in contemporary British politics [PDF]

open access: yes, 2012
This book explores the use of the past in modern British politics. It examines party political perspectives on British history and the historical process, and also looks at the ways in which memory is instituted within the parties in practice, through ...
Cowman, Krista
core  

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

The Future of Civil War History

open access: yes, 2016
In March 2013, hundreds of academics, preservationists, consultants, historical interpreters, museum professionals, living historians, students, K-12 teachers, and new media specialists gathered in Gettysburg, Pennsylvania to assess the state and ...
Broomall, James J.   +2 more
core   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

L’invention des commémorations homosexuelles

open access: yesSocio, 2016
This article focuses on the construction of a homosexual collective memory based on the persecution suffered during World War Two. The analysis of this process shows how a social group, originally stigmatized, succeeded in a relatively short time in ...
Régis Schlagdenhauffen
doaj   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

open access: yesFEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima   +4 more
wiley   +1 more source

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