Results 91 to 100 of about 14,563 (289)
Advanced Science, EarlyView.A self‐regulated Escherichia coli Nissle 1917 strain equipped with a dual‐key genetic circuit achieved antibiotic‐free stability and programmable lysis for therapeutic protein delivery. By co‐expressing an IL‐2 mutant and Amuc_1100, the engineered bacteria restored immune balance and epithelial integrity, providing a safe and precise approach for ...
Shuaijie Ding +6 more
wiley +1 more source
Advancing Precision Nutrition Through Multimodal Data and Artificial Intelligence
Advanced Science, EarlyView.Individual responses to food vary dramatically, challenging traditional dietary advice. This review explores how the unique genetic makeup, gut microbiome, and brain activity shape host metabolic health. We examine how artificial intelligence integrates these multimodal data to predict individualized dietary needs, moving beyond one‐size‐fits‐all ...
Yuanqing Fu +5 more
wiley +1 more source
THE ECOLOGY OF MUTUALISM [PDF]
, 1982 Elementary ecology texts tell us that organisms interact in three fundamen tal ways, generally given the names competition, predation, and mutualism. The third member has gotten short shrift (264), and even its name is not generally agreed on.
Boucher, Douglas H. +2 more
core +1 more source
Plant-associated microorganisms: a view from the scope of microbiology [PDF]
, 2003 Microorganisms interact with plants because plants offer a wide diversity of habitats including the phyllosphere (aerial plant part), the rhizosphere (zone of influence of the root system), and the endosphere (internal transport system).
Montesinos Seguí, Emilio
core +1 more source
Advanced Science, EarlyView.A multifaceted chemical strategy, integrating bacterial tropism, metal‐ion interference therapy, and immunotherapy, resulted in significant tumor regression in murine models. A pioneering paradigm for the design of biohybrid materials was established, highlighting how sophisticated chemical engineering of living systems can unlock new avenues for ...
Tingting Zhang +7 more
wiley +1 more source
Bacterial Outer Membrane Vesicles in Potentiating Cancer Vaccines: Progress and Prospects
Advanced Science, EarlyView.Bacterial outer membrane vesicles (OMVs) have emerged as versatile platforms for cancer vaccine development owing to their intrinsic immunostimulatory properties and high engineering flexibility. This review summarizes OMV biology, immune mechanisms, and engineering strategies that enhance vaccine efficacy, discusses key translational challenges, and ...
Jiabeini Zhang +9 more
wiley +1 more source
Integrating Human Intestinal Organoids into FDA'S New Approach Methodologies for Drug Discovery
Advanced Science, EarlyView.Illustration summarizes how human intestinal organoids (HIOs) are becoming transformative in preclinical research. Preclinical drug discovery pipelines often rely on animal models for ADMET studies, even though interspecies ADME gaps, poor external validity, and high attrition rates are common.
Debarun Patra +6 more
wiley +1 more source
Fire-crested alethes (Alethe castanea) follow humans and bushbuck in Uganda’s Budongo Forest
Frontiers in Bird ScienceThis report documents four observations of a novel foraging behavior in fire-crested alethes (Alethe castanea) in the Budongo Forest Reserve of Western Uganda, where the birds were observed following humans and bushbuck, likely to flush out insect prey ...
Elodie Freymann, Derry Taylor
doaj +1 more source
Bacterial cell-cell communication in the host via RRNPP peptide-binding regulators
Frontiers in Microbiology, 2016 Human microbiomes are composed of complex and dense bacterial consortia. In these environments, bacteria are able to react quickly to change by coordinating their gene expression at the population level via small signaling molecules.
David ePerez-Pascual +3 more
doaj +1 more source
Enhanced Symbiotic Organisms Search (ESOS) for Global Numerical Optimization [PDF]
, 2017 Symbiotic organisms search (SOS) is a simple yet effective metaheuristic algorithm to solve a wide variety of optimization problems. Many studies have been carried out to improve the performance of the SOS algorithm.
Prayogo, Doddy +2 more
core +1 more source