Results 21 to 30 of about 529,022 (270)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
Editor's commentary: Let's know theory!
, 2023 This is the Editor's Commentary on Adlerian Sandtray Therapy as linked to the featured article by Terry Kottman.Counseling, Leadership, Adult Education, and School ...
Homeyer, Linda E.
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Müfessir Fahreddin er-Râzî’nin Meteorolojik Olaylarla İlgili Âyetlere Yaklaşımı
Eskiyeni, 2020 Kur’an, insanlık için bir rehber ve hidayet kaynağı olarak indirilmiş, açık ve anlaşılır bir ilâhî kitap-tır. İndirildiğinden bugüne onun en doğru şekilde anlaşılması, tefsir ilminin ana konusunu oluş-turur.
Abdulkadir Demir
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
A commentary on the popcorn effect [PDF]
Commentary on a serendipitous anecdote in the Journal of Trial of ...
Ross, Wendy
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Prawne aspekty twórczości commentary
Opolskie Studia Administracyjno-Prawne, 2022 Twórczość commentary jest jednym z obecnych trendów w polskim Internecie. Coraz więcej internautów rozpoczyna swoja przygodę z tworzeniem materiałów komentujących, omawiających, a czasem i piętnujących zachowania innych użytkowników Internetu – zwłaszcza
Dominik Gabor
doaj +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source