Results 31 to 40 of about 1,332,237 (287)

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Konstantin Bolshakov in military service: Revisiting the issue [PDF]

open access: yesЛитературный факт, 2019
The note provides a clarifying commentary on the final part of V.I. Mozalevsky’s memoirs “Paths, ways, encounters”. The commentary concerns the Russian poet and prose writer Konstantin Aristarkhovich Bolshakov (1895– 1938) and the details associated with
Nikolay Bogomolov
doaj   +1 more source

Commentary [PDF]

open access: yes, 1974
published or submitted for ...
Martin, Lowell A.
core  

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

Update

open access: yesWorld Nutrition, 2014
The Oslo-Lancet report: global health governance and food security The new Brazilian dietary guide emphasises enjoyment of meals Weston Price, TL Cleave, John Yudkin, the sugar pioneers The real cost of meat.
Commentary team
doaj  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Mulomedicina Chironis 3-15 (la pratica del salasso). Testo critico, traduzione e commento

open access: yesPallas, 2020
Paragraphs 3-15 (concerning the bloodletting of the horse) of the so-called Mulomedicina Chironis are here critically published. An Italian translation and a commentary follow.
Vincenzo Ortoleva
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Commentary [PDF]

open access: yes, 1997
Elsen comments on articles by Deborah DeMott and James Cox. He agrees with them that the rules governing conduct are often different from the rules written in compliance programs and as part of codes of ...
Elsen, Sheldon H.
core   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

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