Results 31 to 40 of about 865,139 (299)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

A Review on the Social History of Islamic Spain in the Historical and Geographical Sources from the Fourth to the Seventh Century After Hijrah [PDF]

تاریخ اسلام, 2012
Andalusia land, separated from the political body of caliphate a little after Islamic conquests, has been the center of attention of historians, geographers, learned people and the other Muslim writers due to its particular climate, historical and ...
Maryam Saeediyan Jazi
doaj  

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Subnational mobilization and political countermovement in EU trade policy in Belgium, Germany and Spain

Paix et Sécurité Internationales
While subnational governments in federal systems are often treated as potentially autonomous policy jurisdictions, central governments have traditionally held exclusive authority over trade policy.
Maria Helena Guimarães, Michelle Egan
doaj   +1 more source

Quelques considérations sur l’histoire du bâtiment théâtral dans les villes danubiennes [PDF]

Studii si Cercetari de Istoria Artei : Teatru, Muzică, Cinematografie, 2012
Vers la fin du XVIe siècle et au début du XVIIe, commence en Europe la construction des bâtiments spécifiquement dédiés au théâtre. En Angleterre et en Espagne, les premiers édifices préservent la structure simple du lieu où on jouait avant : la cour d ...
Daniela Gheorghe
doaj  

Processus d’appropriation et luttes de représentation dans le « Little Jaffna » parisien

Revue Européenne des Migrations Internationales, 2010
The article deals with the La Chapelle area, located between the 10th and 18th districts of Paris, where an increasing number of Tamil shops and associations have grown up over the past twenty or so years.
Gaëlle Dequirez
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Istanbul : le comptoir, le hub, le sas et l’impasse

Revue Européenne des Migrations Internationales, 2003
The Trading Post, the Hub, the Lock and the Dead End.Functions in the International Migratory System. Refusing dominantly used a priori categories such as  irregular  and  regular  migrants-, that seem inadequate and often excessively rigid regarding the
Mustafa Aslan, Jean-François Pérouse
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source