Protonolysis of a Ruthenium–Carbene Bond and Applications in Olefin Metathesis [PDF]
The synthesis of a ruthenium complex containing an N-heterocylic carbene (NHC) and a mesoionic carbene (MIC) is described wherein addition of a Brønsted acid results in protonolysis of the Ru–MIC bond to generate an extremely active metathesis catalyst ...
Bertrand, Guy +3 more
core +3 more sources
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Online learning : towards enabling choice [PDF]
Education is rapidly evolving from an opportunity that was provided mainly for an elite to one that is available to a mass markets and as such is prone to the forces generated by this environment.
Ferguson, John D. +2 more
core
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
IMPROVING THE ORGANIZATIONAL AND ECONOMIC MECHANISM OF COMMERCIAL ACTIVITIES MANAGEMENT
The research is devoted to the development of measures aimed at improving the organizational and economic mechanism of commercial activities of medium- and large-scale commercial organizations in Ukraine.
B. M. Mizyuk +2 more
doaj
Enzymatic pretreatment of microalgae using fungal broth from Trametes versicolor and commercial laccase for improved biogas production [PDF]
Coupling microalgae production to wastewater treatment can reduce the costs of microalgae production for non-food bioproducts and energy consumption for wastewater treatment.
Blánquez, Paqui +4 more
core +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Activization of Innovative Activities of Russian Commercial Banks
In the article the authors use systemic and historic analysis to determine the significant stages of formation and development of the Russian banking system. The authors study the monetary policy of the Bank of Russia and substantiate its influence on activization of innovative activities of commercial banks which determined the stability and ...
Olesya A. Stroeva +3 more
openaire +2 more sources
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
The essence and development of electronic commerce in Ukraine: an accounting aspect
The essence and features of electronic commerce in the world and in Ukraine under modern conditions have been observed in the article. The advantages and disadvantages of electronic commerce, development prospects and favorable factors of impact have ...
Y.P. Kvach, O.G. Drozdova
doaj

