Results 61 to 70 of about 423,978 (260)

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Analysis of yield-attributing traits for high-yielding wheat lines in southwestern Japan

Plant Production Science, 2016
Development of wheat cultivars that achieve high yields despite the short growing season is essential for increasing wheat production in southwestern Japan.
Midori Okami, Hitoshi Matsunaka, Masaya Fujita, Kazuhiro Nakamura, Zenta Nishio   +4 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Biometry and carcass characteristics of lambs supplemented in tropical grass pastures during the dry season

Bioscience Journal, 2017
The objective of this study was to evaluate the biometry and carcass characteristics of finished Santa Inês crossbred sheep grazed on tropical grass pastures during the dry season.
Thiago Felipe de Medeiros Trindade, Gelson dos Santos Difante, João Virgínio Emerenciano Neto, Leonardo Santana Fernandes, Itânia Maria Medeiros de Araújo, Emmanuel Lievio de Lima Véras, Marcone Geraldo Costa, Maria Gabriela da Trindade Silva, Mariana Campelo Medeiros   +8 more
doaj   +3 more sources

Challenges and insights in UAV-based tomato yield estimation in commercial plasticulture systems

Discover Agriculture
Advances in UAV remote sensing have prompted the exploration of phenotypic traits, such as canopy area, for timely yield assessments. However, conducting UAV-based yield assessments in large commercial fields under variable weather conditions remains ...
Mehran Homayounfar, Hadi Ghaderian, Gregory S. Hendricks, Vijay P. Santikari, Justin Schabow, Sanjay Shukla   +5 more
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Agronomic performance of experimental strawberry clones in southern Minas Gerais

Revista Agrogeoambiental
In Brazil, there is a great dependence on strawberry seedlings imported from other countries, as demand is higher than national production. This study was developed in order to evaluate the agronomic performance of experimental strawberry clones for the
Ronivaldo Crispim da Veiga Junior, Marcos Rian dos Santos, Marcelo Henrique Avelar Mendes, Luciane Vilela Resende, Sindynara Ferreira   +4 more
doaj   +1 more source

The importance of multi-year studies and commercial yield metrics in measuring pollinator dependence ratios: A case study in UK raspberries Rubus idaeus L. [PDF]

Ecol Evol, 2023
Ryan IC, Dicks LV, Shutt JD.
europepmc   +1 more source